Cover Image, Volume 131, Issue 4



The semicrystalline polymer, poly(L-lactic acid) (PLLA), is used to fabricate scaffolds by thermally induced phase separation (TIPS) for various engineering applications in tissues such as bone, nerve, and cartilage. Liumin He et al. use PLLA to prepare a 3D fibrous network with nanoscale fiber diameters. The physicochemical properties of the solvent and polymer together influence the properties of the solution and the thermodynamic development upon quenching. The crystallization behavior of PLLA further affects cell growth in the scaffold. The cover shows a microscopy image of the PLLA scaffolds. This first system investigation provides a valuable reference for scaffold fabrication and its application in tissue engineering. DOI: 10.1002/app.39436