Surface modification of electrospun chitosan nanofibrous mats for antibacterial activity
Article first published online: 28 MAY 2014
Copyright © 2014 Wiley Periodicals, Inc.
Journal of Applied Polymer Science
Volume 131, Issue 21, November 5, 2014
How to Cite
2014), Surface modification of electrospun chitosan nanofibrous mats for antibacterial activity. J. Appl. Polym. Sci., 131, 40981, doi: 10.1002/app.40981, , and (
- Issue published online: 11 AUG 2014
- Article first published online: 28 MAY 2014
- Manuscript Accepted: 28 APR 2014
- Manuscript Received: 27 DEC 2013
- Thailand Research Fund and the Commission of Higher Education
- Ministry of Education for funding the research under the Senior Scholarly Consolidation . Grant Number: RTA5080004
- antibacterial activity;
- nanostructured polymers
Chitosan (CS) blended with poly(ethylene oxide) (PEO) was electrospun into nanofibrous mats. The spinning solution of 6.7 : 0.3 (% w/v) of CS : PEO was dissolved in a 70 : 30 (v/v) trifluoroacetic acid/dichloromethane solution. The obtained fibers were smooth without beads on their surfaces and average diameter of the fiber was 272 ± 56 nm. N-(2-hydroxyl) propyl-3-trimethyl ammonium chitosan chloride (HTACC) and N-benzyl-N,N-dimethyl chitosan iodide (QBzCS) were each prepared from the CS/PEO mats. They were identified by Fourier-transform infrared and X-ray photoelectron spectroscopy and degree of swelling in water. Both quaternized electrospun chitosan mats exhibited superior antibacterial activity to the unmodified electrospun CS/PEO against Staphylococcus aureus and Escherichia coli at short contact times. After 4 h of contact, the reduction of both bacterial strains by CS/PEO, HTACC, and QBzCS was equal at about 99–100%. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40981.