Hypophysis-thyroid system in the fetal rat: Thyroid after hypophyseoprivia, thyroxin, thriiodothyronine, thyrotrophin and growth hormone§


  • Part of this paper is an abridgement of a thesis submitted by Ung Kee Hwang to the faculty of the Graduate School in partial fulfillment of the requirements for the degree of Ph.D. in Anatomy.

  • Aided by grants from the National Institutes of Health (A–1244) and from the Medical Research Fund of the Graduate School.

  • §

    The authors are indebted: (a) to Prof. C. H. Li of the University of California for the growth hormone, Lot L2394A, (b) to Dr. Arthur E. Heming of Smith, Klein and French Laboratories for the triiodothyronine, Lot L2323, which had been synthesized by the Glaxo Laboratories, (c) to Dr. J. Murray Scott for Ayerst, McKenna and Harrison's thyrotropic Factor, Lot 456, 50 TSH units per ml, (d) to Dr. Edwin E. Hays for Armour's thyrotrophin, Lot 2-cr-3, and (e) to Miss Marion Anderson, Junior Scientist, and Mrs. Junita Mortensen and Mrs. Marie Lucas, Technologists, for special technical assistance.

  • The thyroxin was purchased in the form of tablets (E. R. Squibb and Sons, List 9425).