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Abstract

The epidermis of the potto, which normally contains no DOPA-reactive melanotic melanocytes, supports a population of large dendritic cells which are specifically reactive for alkaline phosphatase. After irradiation of the skin with ultraviolet light, these same dendritic cells become DOPA positive and produce visible melanin. These results give further evidence that the alkaline phosphatase-reactive dendritic cells are part of a unique system of epidermal melanocytes.