This investigation was supported in whole by Public Health Service Research grants GM-04433 from the National Institute of General Medical Sciences and DE-01894 from the National Institute of Dental Research.
Development of mouse pubic joint in vivo following initial differentiation in vitro†
Version of Record online: 3 FEB 2005
Copyright © 1965 Wiley-Liss, Inc.
The Anatomical Record
Volume 153, Issue 2, pages 161–171, October 1965
How to Cite
Crelin, E. S. and Koch, W. E. (1965), Development of mouse pubic joint in vivo following initial differentiation in vitro. Anat. Rec., 153: 161–171. doi: 10.1002/ar.1091530206
- Issue online: 3 FEB 2005
- Version of Record online: 3 FEB 2005
Typical immature pubic joints developed when undifferentiated mesenchyme from the pelvic region of 13-day-old embryos was grown in vitro on a Millipore filter. After five days the joints were transplanted to 5-day-old postnatal female mice whose pubic joints were excised prior to transplantation. The transplanted joints developed to adult-type symphyses and replaced the excised joints of the recipients. Typical bone resorption and cartilage transformation to ligamentous tissue occurred in transplanted joints in pregnant recipients.