Supported by a Rockefeller Foundation Fellowship.
Correlation of localization of alkaline and acid phosphatases with morphological development of the rat kidney†
Article first published online: 3 FEB 2005
Copyright © 1966 Wiley-Liss, Inc.
The Anatomical Record
Volume 154, Issue 2, pages 253–259, February 1966
How to Cite
Desalu, A. B. O. (1966), Correlation of localization of alkaline and acid phosphatases with morphological development of the rat kidney. Anat. Rec., 154: 253–259. doi: 10.1002/ar.1091540208
- Issue published online: 3 FEB 2005
- Article first published online: 3 FEB 2005
The Gomori (metal-salt) and azo-dye techniques were used for the localization of alkaline and acid phosphatases in the metanephric kidneys from 13- to 22-day-old fetal rats. Alkaline phosphatase activity was localized first in the luminal (brush) border of the differentiated proximal tubule in the kidneys of 19-day-old fetuses. Acid phosphatase activity was first localized in the cytoplasm of all the morphologically differentiated cells of the nephron in the kidneys of 20-day-old fetuses as cytoplasmic “droplets.” The relationships of the localization of these to the morphological differentiation of the nephron is discussed.