This investigation was begun in the Department of Zoology, Louisiana State University, Baton Rouge, Louisiana, with the support of grant G-14153–GB271 of the National Science Foundation. The work was concluded at the University of Richmond through the aid of NSF grant GB2721.
Regulation of pigment cell colonization of PET mouse leg muscles†
Article first published online: 23 FEB 2005
Copyright © 1966 Wiley-Liss, Inc.
The Anatomical Record
Volume 155, Issue 1, pages 89–95, May 1966
How to Cite
Reams, W. M. (1966), Regulation of pigment cell colonization of PET mouse leg muscles. Anat. Rec., 155: 89–95. doi: 10.1002/ar.1091550110
- Issue published online: 23 FEB 2005
- Article first published online: 23 FEB 2005
The results of autoplastic and homoplastic transplants of PET mouse tissues indicate that the state of differentiation of the developing muscles limits the extent of invasion by pigment cells of the muscles of the leg in PET mice. Additionally, intracoelomic grafts into host chick embryos of PET mouse leg tissues has given evidence which suggests that the pigment cell behavior is affected also by a restriction of pigment cell proliferation and concurrent migration by the initiation of pigment cell morphogenesis. Thus it appears that the colonization of the leg muscles by pigment cells in the PET mouse is governed both by the structural limitations and morphogenetic influence imposed upon the melanoblasts by the tissue substrate.