This study was supported in part by grant no. 1-F2-HD-15, 46-01, National Institute of Child Health and Human Development.
Annulated lamellae in the ductus epididymidis of fetal and castrated adult rats†
Article first published online: 3 FEB 2005
Copyright © 1968 Wiley-Liss, Inc.
The Anatomical Record
Volume 161, Issue 4, pages 427–440, August 1968
How to Cite
Van De Velde, R. L. and Van De Velde, S. C. (1968), Annulated lamellae in the ductus epididymidis of fetal and castrated adult rats. Anat. Rec., 161: 427–440. doi: 10.1002/ar.1091610404
- Issue published online: 3 FEB 2005
- Article first published online: 3 FEB 2005
A consistent feature of epithelial cells lining the initial segment of the ductus epididymidis of rats bilaterally castrated for about three months is the presence of stacks of annulated lamellae. They were occasionally observed by two months following gonadectomy but were not evident in one-month castrates nor in normal controls or unilaterally orchiectomized rats.
Observation of epididymides from neonatal and fetal rats taken at daily intervals between the twelfth and twenty-first day following conception demonstrated that small and inconspicuous annulated lamellae occurred normally during differentiation. They were observed on several occasions in widely scattered cells during the fifteenth day of gestation.
In the epididymis, annulated membranes may form from the outer nuclear membrane by a process of budding. The annulated membrane complex is “destroyed” in long term castrates following the subcutaneous injection of testosterone proprionate.