Origin of amphibian premelanosomes and their relation to microtubules



In amphibian melanophores, premelanosomes appear to be formed in fenestrated cisternae of the Golgi complex. The premelanosomes may develop within the cisternae or vesicles containing melanoprotein may bud from the cisternae to form premelanosomes. Some micrographs also demonstrate a close association between microtubules and either premelanosomes or melanosomes. The microtubules themselves may originate from electron dense particles in the centrosphere region of the cell.