The author wishes to acknowledge the technical assistance of Mrs. Stephanie Krah.
Extracellular specializations associated with hemidesmosomes in the fetal rat urogenital sinus†
Article first published online: 27 JAN 2005
Copyright © 1970 Wiley-Liss, Inc.
The Anatomical Record
Volume 168, Issue 2, pages 195–202, October 1970
How to Cite
Flickinger, C. J. (1970), Extracellular specializations associated with hemidesmosomes in the fetal rat urogenital sinus. Anat. Rec., 168: 195–202. doi: 10.1002/ar.1091680206
This study was supported by contract 69-2104 with the National Institutes of Health, Program Project HD-02282 of the National Institutes of Health, Health Sciences Advancement Award FR-02084 from the National Institutes of Health, and a Research Career Development Award (1-K3-GM-28, 214-01) from the National Institute of General Medical Sciences.
- Issue published online: 27 JAN 2005
- Article first published online: 27 JAN 2005
- Manuscript Accepted: 15 MAY 1970
- Manuscript Received: 16 FEB 1970
Specializations of extracellular structures opposite hemidesmosomes at the basal surface of epithelial cells of the fetal rat urogenital sinus are described. A moderately dense band or lamella ∼ 100 Å wide forms a cap about 50 Å from the plasma membrane. The normally electron-lucent inner zone between the plasma membrane and the basal lamina is increased in density and may be traversed by filaments or strands of material extending from the cell surface. The basal lamina is thickened and its density is increased locally opposite hemidesmosomes. The possible role of these specializations in adhesion between epithelial cells and the underlying extra-cellular structures is considered.