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Abstract

The epithelium in the region of the vaginal introitus in the rat (“introital epithelium”) was examined in sexually mature animals in different stages of the estrous cycle. It was found to be stratified squamous in type and invariably cornified, irrespective of the state of the vaginal epithelium above it. Thus, it failed to undergo the estrous cyclic changes seen in the rest of the vaginal epithelium. The introital epithelium extends for a distance of 1.5 to 5 mm above the vaginal orifice.