Prolonged survival of fragments of liver transplanted to an ectopic site in the mouse



Fragments of liver were successfully transplanted to an ectopic site in the kidney cortex of the mouse. Survival was followed for varying periods of time. In some cases both syngeneic grafts and allogeneic grafts placed in mice previously made immunologically tolerant to the genotype of the donor were still alive one year later. However, extensive amounts of liver tissue would not survive, at the best, strips of about 30 cells thick grew, and various measures tried to promote an increase in this amount were not successful.