This work was supported by NIDR Grant 1 ROL DE04695-01.
Extracellular coat in developing human palatal processes: Electron microscopy and ruthenium red binding†
Version of Record online: 26 JAN 2005
Copyright © 1978 Wiley-Liss, Inc.
The Anatomical Record
Volume 190, Issue 2, pages 223–231, February 1978
How to Cite
Meller, S. M. and Barton, L. H. (1978), Extracellular coat in developing human palatal processes: Electron microscopy and ruthenium red binding. Anat. Rec., 190: 223–231. doi: 10.1002/ar.1091900206
- Issue online: 26 JAN 2005
- Version of Record online: 26 JAN 2005
- Manuscript Accepted: 29 AUG 1977
- Manuscript Received: 5 APR 1977
The prefusion epithelium of human palatal processes was examined for evidence of specialization which might facilitate epithelial adherence with the opposing palatal process. A surface coat stained with ruthenium red (RR) was found on all apical aspects of the palatal epithelium. In the prefusion regions, RR staining was also observed in the spaces between the superficial cells of the epithelium and in necrotic cells. Adjacent oral and nasal epithelium excluded the RR below the level of the apical junctional complex. In the absence of RR, a dense material was observed in the most superficial intercellular spaces of the prefusion region. Many superficial cells in the area were in various stages of necrosis. The combination of degenerating surface cells and an accumulation of a poly-anionic substance such as glycoprotein may facilitate epithelial adherence between opposing human palatal processes.