This work was supported by the National Institute of Environ mental Health Sciences and the US. Department of Energy under Contract EY-76-C-04-1013 and conducted in animal care facilities fully accredited by the American Association for Accreditation of Laboratory Animal Care.
Anatomic Models of the tracheobronchial and pulmonary regions of the rat†
Article first published online: 2 FEB 2005
Copyright © 1979 Wiley-Liss, Inc.
The Anatomical Record
Volume 195, Issue 3, pages 483–492, November 1979
How to Cite
Yeh, H. C., Schum, G. M. and Duggan, M. T. (1979), Anatomic Models of the tracheobronchial and pulmonary regions of the rat. Anat. Rec., 195: 483–492. doi: 10.1002/ar.1091950308
- Issue published online: 2 FEB 2005
- Article first published online: 2 FEB 2005
- Manuscript Accepted: 14 JUN 1979
- Manuscript Received: 1 FEB 1979
Models of the lung airways of a rat were developed from complete measurements of the tracheobronchial airways. A silicone rubber cast of the tracheobronchial airways of a rat lung was prepared and all individual airway segments down to and including the terminal bronchioles were measured to obtain the segment diameters, lengths, branching angles and angles of inclination to gravity. Models of the rat tracheobronchial airways were constructed based on the original measurements and the subsequent analysis. Some mathematical assumptions about acinar anatomy distal to terminal bronchioles were made to extend the models to include pulmonary regions. Emphasis was placed on the “Typical Path Lung Model” which used one typical pathway to represent either a whole lung or a lobe of the lung. The models are simple and can be applied in calculation of physiologic variables or particle deposition during inhalation in various lobes of the lung.