Hematology and Immunology
Effects of orchidectomy on the adrenal macrophage system
Article first published online: 26 JAN 2005
Copyright © 1980 Wiley-Liss, Inc.
The Anatomical Record
Volume 198, Issue 2, pages 209–218, October 1980
How to Cite
Maglhães, M. M. and Magalhães, M. C. (1980), Effects of orchidectomy on the adrenal macrophage system. Anat. Rec., 198: 209–218. doi: 10.1002/ar.1091980208
- Issue published online: 26 JAN 2005
- Article first published online: 26 JAN 2005
- Manuscript Accepted: 7 FEB 1980
- Manuscript Received: 2 JUL 1979
Macrophages of the adrenal cortex were studied in normal and orchidectomized rats. In normal rats, few macrophages with numerous cytoplasmic granules were observed, mainly in the zona reticularis. Granules were limited by a single membrane and contained either a finely granular dense matrix or heterogeneous materials made up of electron-lucent parts, dark granular and membranous areas. An aminotriazole-resistant peroxidatic activity was confined to the dense granules. In orchidectomized rats, the number of macrophages was markedly increased, and the cells were concentrated at the border between the zonae fasciculata and reticularis and disseminated throughout the zona reticularis. Lysosomes were more numerous in each macrophage, and those of heterogeneous matrix were larger and their contents were more complex than in normal rats. These results show that orchidectomy stimulates the adrenal macrophage system.