Filamentary rod-shaped granules in clara cells of rats
Article first published online: 26 JAN 2005
Copyright © 1981 Wiley-Liss, Inc.
The Anatomical Record
Volume 201, Issue 2, pages 283–291, October 1981
How to Cite
Baert, J. and Vandenberghe, M. P. (1981), Filamentary rod-shaped granules in clara cells of rats. Anat. Rec., 201: 283–291. doi: 10.1002/ar.1092010208
- Issue published online: 26 JAN 2005
- Article first published online: 26 JAN 2005
- Manuscript Accepted: 10 APR 1981
- Manuscript Received: 15 JAN 1981
The bronchiolar Clara cells of rats contain characteristic rodshaped granules always surrounded by a unit membrane. These granules contain thin filaments about 9 to 10 nm in diameter lying in a pale matrix. Our morphological results suggest that the filamentary rod-shaped granules originate from the common, round-to-oval, electron-dense Clara cell granules, as we found different intermediate structures between these two kinds of granules. The electron-dense granules are digested by pepsin, whereas the filamentary rod-shaped granules are apparently not affected. The biochemical nature and the possible function of the filamentary rod-shaped granules are also discussed in relation to the secretory activity of the Clara cells.