Effects of chronic denervation in type I cutaneous mechanoreceptors (Haarscheiben)
Article first published online: 8 FEB 2005
Copyright © 1983 Wiley-Liss, Inc.
The Anatomical Record
Volume 207, Issue 1, pages 79–88, September 1983
How to Cite
English, K. B., Norman, D. K.-V. and Horch, K. (1983), Effects of chronic denervation in type I cutaneous mechanoreceptors (Haarscheiben). Anat. Rec., 207: 79–88. doi: 10.1002/ar.1092070109
- Issue published online: 8 FEB 2005
- Article first published online: 8 FEB 2005
- Manuscript Accepted: 27 APR 1983
- Manuscript Received: 30 JUN 1982
Cutaneous type I receptor sites (Haarscheiben or tactile domes) were examined at intervals of 4 to 275 days after chronic denervation of the skin. The number of domes decreased with denervation time, and only about one-third of the domes originally present were still visible at 275 days. Most but not all of the Merkel cells from these domes were absent by 48 days, and the epithelium was significantly thinner than in nondenervated domes. Only a few of the examined domes appeared to be completely devoid of Merkel cells.
It is concluded that after nerve transection, domes degenerate but do not always disappear entirely. The remmants may thus act as target sites which either attract regenerating type I nerve fibers or facilitate the formation of new dome structures after nerve regeneration.