Cell proliferation in chick oral membrane lags behind that of adjacent epithelia at the time of rupture
Article first published online: 26 JAN 2005
Copyright © 1989 Wiley-Liss, Inc.
The Anatomical Record
Volume 223, Issue 2, pages 204–208, February 1989
How to Cite
Miller, S. A. and Olcott, C. W. (1989), Cell proliferation in chick oral membrane lags behind that of adjacent epithelia at the time of rupture. Anat. Rec., 223: 204–208. doi: 10.1002/ar.1092230213
- Issue published online: 26 JAN 2005
- Article first published online: 26 JAN 2005
- Manuscript Accepted: 20 JUL 1988
- Manuscript Received: 28 SEP 1987
Radioautographic analysis showed that ectoderm and endoderm cells in chick oral membrane continued to label with tritiated thymidine through the period of rupture, but their frequency of labeling was significantly lower than those of adjacent epithelia. Frequency of labeling increased in adjacent ectoderm and endoderm, while oral membrane rates remained relatively low, suggesting that growth in the membrane lags relative to adjacent epithelia. Relatively greater proliferation in adjacent epithelia could generate tension and pull apart the thinned oral membrane. Differentials in rates of cell proliferation, when considered along with knowledge of cellular rearrangements following changes in basal lamina and matrical components, suggest that differential growth is an important force in rupture of the avian oral membrane.