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  • Chieffi P, Cozzolino L, Kisslinger A, Libertini S, Staibano S, Mansueto G, De Rosa G, Villacci A, Vitale M, Linardopoulos S, Portella G, Tramontano D. 2006. Aurora B expression directly correlates with prostate cancer malignancy and influence prostate cell proliferation. Prostate 66: 326333.
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  • Di Gennaro E, Barbarino M, Bruzzese F, De Lorenzo S, Caraglia M, Abbruzzese A, Avallone A, Comella P, Caponigro F, Pepe S, Budillon A. 2003. Critical role of both p27Kip1 and p21Cip1/Waf1 in the antiproliferative effect of ZD1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells. J Cell Physiol 195: 139150.
  • Han X, Chen S, Sun Y, Nadler JL, Bleich D. 2002. Induction of cyclooxygenase-2 gene in pancreatic beta-cells by 12-lipoxygenase pathway product 12-hydroxyeicosatetraenoic acid. Mol Endocrinol 16: 21452154.
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  • Keen N, Taylor S. 2004. Aurora-kinase inhibitors as anticancer agents. Nat Rev Cancer 4: 927936.
  • Kindler HL. 2005. Front-line therapy of advanced pancreatic cancer. Semin Oncol 32: S33S36.
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  • Koyama M, Matsuzaki Y, Yogosawa S, Hitomi T, Kawanaka M, Sakai T. 2007. ZD1839 induces p15Ink4b and causes G1 arrest by inhibiting the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway. Mol Cancer Ther 6: 15791587.
  • Kurai M, Shiozawa T, Shih HC, Miyamoto T, Feng YZ, Kashima H, Suzuki A, Konishi I. 2005. Expression of Aurora kinases A and B in normal, hyperplastic, and malignant human endometrium: aurora B as a predictor for poor prognosis in endometrial carcinoma. Hum Pathol 36: 12811288.
  • Li J, Kleeff J, Giese N, Büchler MW, Korc M, Friess H. 2004. Gefitinib ('Iressa', ZD1839), a selective epidermal growth factor receptor tyrosine kinase inhibitor, inhibits pancreatic cancer cell growth, invasion, and colony formation. Int J Oncol 25: 203210.
  • Sgambato A, Camerini A, Faraglia B, Ardito R, Bianchino G, Spada D, Boninsegna A, Valentini V, Cittadini A. 2004. Targeted inhibition of the epidermal growth factor receptor-tyrosine kinase by ZD1839 ('Iressa') induces cell-cycle arrest and inhibits proliferation in prostate cancer cells. J Cell Physiol 201: 97105.
  • Shintani S, Li C, Mihara M, Yano J, Terakado N, Nakashiro K, Hamakawa H. 2004. Gefitinib ('Iressa', ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, up-regulates p27Kip1 and induces G1 arrest in oral squamous cell carcinoma cell lines. Oral Oncol 40: 4351.
  • Sorrentino R, Libertini S, Pallante PL, Troncone G, Palombini L, Bavetsias V, Spalletti-Cernia D, Laccetti P, Linardopoulos S, Chieffi P, Fusco A, Portella G. 2005. Aurora B overexpression associates with the thyroid carcinoma undifferentiated phenotype and is required for thyroid carcinoma cell proliferation. J Clin Endocrinol Metab 90: 928935.
  • Tracy S, Mukohara T, Hansen M, Meyerson M, Johnson BE, Jänne PA. 2004. Gefitinib induces apoptosis in the EGFRL858R non-small-cell lung cancer cell line H3255. Cancer Res 64: 72417244.
  • Woodburn JR, Morris CQ, Kelly H, Laight A. 1998. EGF receptor tyrosine kinase inhibitors as anti-cancer agents–preclinical and early clinical profile of ZD1839. Cell Mol Biol Lett 3: 348349.
  • Wu X, Rubin M, Fan Z, DeBlasio T, Soos T, Koff A, Mendelsohn J. 1996. Involvement of p27Kip1 in G1 arrest mediated by an anti-epidermal growth factor receptor monoclonal antibody. Oncogene 12: 13971403.
  • Ye D, Mendelsohn J, Fan Z. 1999. Androgen and epidermal growth factor down-regulate cyclin-dependent kinase inhibitor p27Kip1 and costimulate proliferation of MDA PCa2a and MDA PCa2b prostate cancer cells. Clin Cancer Res 5: 21712177.
  • Zeng WF, Navaratne K, Prayson RA, Weil RJ. 2007. Aurora B expression correlates with aggressive behaviour in glioblastoma multiforme. J Clin Pathol 60: 218221.