Ecto-5′-Nucleotidase-Positive Cells in the Choroid and Ciliary Body of the Rat Eye
Version of Record online: 20 JAN 2010
Copyright © 2010 Wiley-Liss, Inc.
The Anatomical Record
Volume 293, Issue 3, pages 379–382, March 2010
How to Cite
Braun, J. S. (2010), Ecto-5′-Nucleotidase-Positive Cells in the Choroid and Ciliary Body of the Rat Eye. Anat Rec, 293: 379–382. doi: 10.1002/ar.21080
- Issue online: 17 FEB 2010
- Version of Record online: 20 JAN 2010
- Manuscript Accepted: 15 SEP 2009
- Manuscript Revised: 13 SEP 2009
- Manuscript Received: 22 AUG 2008
- ciliary body;
Adenosine is known to exert multiple functions within the eye. The aim of this report was to find out if adenosine can be produced locally in the choroid and ciliary body. Therefore, I investigated the distribution of ecto-5′-nucleotidase (5′-NT), the key enzyme for the production of extracellular adenosine. This report provides evidence that 5′-NT is expressed in the choroid and in the ciliary body (and its processes) of the rat eye, predominantly in endothelial cells. These locations of 5′-NT indicate strategically important production sites of adenosine regulating choroid and ciliary body functions (e.g., blood flow, aqueous fluid production, and immune response). Anat Rec, 2010. © 2010 Wiley-Liss, Inc.