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LITERATURE CITED

  • Adeva M, El-Youssef M, Rossetti S, Kamath PS, Kubly V, Consugar MB, Milliner DM, King BF, Torres VE, Harris PC. 2006. Clinical and molecular characterization defines a broadened spectrum of autosomal recessive polycystic kidney disease (ADPKD). Medicine (Baltimore) 85: 121.
  • Bergmann C, Senderek J, Sedlacek B, Pegiazoglou I, Puglia P, Eggermann T, Rudnik-Schöneborn S, Furu L, Onuchic LF, De Baca M, Germino GG, Guay-Woodford L, Somlo S, Moser M, Büttner R, Zerres K. 2003. Spectrum of Mutations in the Gene for Autosomal Recessive Polycystic Kidney Disease (ARPKD/PKHD1). J Am Soc Nephrol 14: 7689.
  • Brown NE, Murcia NS. 2003. Delayed cystogenesis and increased ciliogenesis associated with the re-expression of polaris in Tg737 mutant mice. Kidney Int 63: 12201229.
  • Furu L, Onuchic LF, Gharavi A, Hou X, Esquivel EL, Nagasawa Y, Bergmann C, Senderek J, Avner E, Zerres K, Germino GG, Guay-Woodford LM, Somlo S. 2003. Milder presentation of recessive polycystic kidney disease requires presence of amino acid substitution mutations. J Am Soc Nephrol 14: 20042014.
  • Gallagher AR, Esquivel EL, Briere TS, Tian X, Mitobe M, Menezes LF, Markowitz GS, Jain D, Onuchic LF, Somlo S. 2008. Biliary and pancreatic dysgenesis in mice harboring a mutation in Pkhd1. Am J Pathol 172: 417429.
  • Gattone VH, Wang X, Harris PC, Torres VE. 2003. Inhibition of renal cystic disease development and progression by a vasopressin V2 receptor antagonist. Nat Med 9: 13231326
  • Gattone VH, Sinders RM, Hornberger TA, Robling AG. 2009 Late progression of renal pathology and cyst enlargement is reduced by rapamycin in a mouse model of nephronophthisis. Kidney Int 76: 178182.
  • Guay-Woodford LM. 1996. Autosomal recessive polycystic kidney disease: clinical and genetic profiles. In Polycystic Kidney Disease. Oxford, UK: Oxford Medical Publications.
  • Katsuyama M, Masuyama T, Komura I, Hibino T, Takahashi H. 2000. Characterization of a novel polycystic kidney rat model with accompanying polycystic liver. Exp Anim 49: 5155.
  • Lager DJ, Qian Q, Bengal RJ, Ishibashi M, Torres VE. 2001. The PCK rat: a new model that resembles human autosomal dominant polycystic kidney and liver disease. Kidney Int 59: 126136.
  • Lin F, Hiesberger T, Cordes K, Sinclair AM, Goldstein LS, Somlo S, Igarashi P. 2003. Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease. Proc Natl Acad Sci USA 100: 52865291.
  • Masyuk TV, Huang BQ, Ward CJ, Masyuk AI, Yuan D, Splinter PL, Punyashthiti R, Ritman EL, Torres VE, Harris PC, LaRusso NF. 2003. Defects in cholangiocyte fibrocystin expression and ciliary structure in the PCK rat. Gastroenterology 125: 13031310.
  • Masyuk TV, Huang BQ, Masyuk AI, Ritman EL, Torres VE, Wang X, Harris PC, Larusso NF. 2004. Biliary dysgenesis in the PCK rat, an orthologous model of autosomal recessive polycystic kidney disease. Am J Pathol 165: 17191730.
  • Masyuk TV, Masyuk AI, Torres VE, Harris PC, Larusso NF. 2007. Octreotide inhibits hepatic cystogenesis in a rodent model of polycystic liver disease by reducing cholangiocyte adenosine 3′,5′-cyclic monophosphate. Gastroenterology 132: 11041116.
  • Moe SM, Chen NX, Seifert MF, Sinders RM, Duan D, Chen X, Liang Y, Radcliff JS, White KE, Gattone VH 2nd. 2009. A rat model of chronic kidney disease-mineral bone disorder. Kidney Int 75: 176184.
  • Nagao S, Nishii K, Katsuyama M, Kurahashi H, Marunouchi T, Takahashi H, Wallace DP. 2006. Increased water intake decreases progression of polycystic kidney disease in the PCK rat. J Am Soc Nephrol 17: 22202227.
  • Nyengaard JR. 1999. Stereologic methods and their application in kidney research. J Am Soc Nephrol 10: 11001123.
  • Sanzen T, Harada K, Yasoshima M, Kawamura Y, Ishibashi M, Nakanuma Y. 2001. Polycystic kidney rat is a novel animal model of Caroli's disease associated with congenital hepatic fibrosis. Am J Pathol 158: 16051612.
  • Sato Y, Harada K, Furubo S, Kizawa K, Sanzen T, Yasoshima M, Ozaki S, Isse K, Sasaki M, Nakanuma Y. 2006. Inhibition of intrahepatic bile duct dilation of the polycystic kidney rat with a novel tyrosine kinase inhibitor gefitinib. Am J Pathol 169: 12381250.
  • Torres VE, Sweeney WE, Jr., Wang X, Qian Q, Harris PC, Frost P, Avner ED. 2003. EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats. Kidney Int 64: 15731579.
  • Torres VE, Sweeney WE, Jr., Wang X, Qian Q, Harris PC, Frost P, Avner ED. 2004. Epidermal growth factor receptor tyrosine kinase inhibition is not protective in PCK rats. Kidney Int 66: 17661773.
  • Torres VE, Harris, P, Pirson, Y. 2007. Autsomal dominant polycystic kidney disease. The Lancet 369: 12871301.
  • Wang S, Luo Y, Wilson PD, Witman GB, Zhou J. 2004 The autosomal recessive polycystic kidney disease protein is localized to primary cilia, with concentration in the Basal body area. J Am Soc Nephrol 15: 592602
  • Wang X, Gattone V, II, Harris PC, Torres VE. 2005. Effectiveness of vasopressin V2 receptor antagonists OPC-31260 and OPC-41061 on polycystic kidney disease development in the PCK rat. J Am Soc Nephrol 16: 846851.
  • Wang X, Wu Y, Ward CJ, Harris PC, Torres VE. 2008. Vasopressin directly regulates cyst growth in polycystic kidney disease. J Am Soc Nephrol 19: 102108.
  • Ward CJ, Hogan MC, Rossetti S, Walker D, Sneddon T, Wang X, Kubly V, Cunningham JM, Bacallao R, Ishibashi M, Milliner DS, Torres VE, Harris PC. 2002. The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein. Nat Genet 30: 259269.
  • Ward CJ, Yuan D, Masyuk TV, Wang X, Punyashthiti R, Whelan S, Bacallao R, Torra R, LaRusso NF, Torres VE, Harris PC. 2003 Cellular and subcellular localization of the ARPKD protein; fibrocystin is expressed on primary cilia. Hum Mol Genet 12: 27032710.
  • Williams SS, Cobo-Stark P, James LR, Somlo S, Igarashi P. 2008. Kidney cysts, pancreatic cysts, and biliary disease in a mouse model of autosomal recessive polycystic kidney disease. Pediatr Nephrol 23: 733741.
  • Woollard JR, Punyashtiti R, Richardson S, Masyuk TV, Whelan S, Huang BQ, Lager DJ, vanDeursen J, Torres VE, Gattone VH, LaRusso NF, Harris PC, Ward CJ. 2007. A mouse model of autosomal recessive polycystic kidney disease with biliary duct and proximal tubule dilatation. Kidney Int 72: 328336.
  • Zhang MZ, Mai W, Li C, Cho SY, Hao C, Moeckel G, Zhao R, Kim I, Wang J, Xiong H, Wang H, Sato Y, Wu Y, Nakanuma Y, Lilova M, Pei Y, Harris RC, Li S, Coffey RJ, Sun L, Wu D, Chen XZ, Breyer MD, Zhao ZJ, McKanna JA, Wu G. 2004. PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells. Proc Natl Acad Sci USA 101: 23112316.