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LITERATURE CITED

  • Chan L, Terashima T, Fujimiya M, Kojima H. 2006. Chronic diabetic complications: the body's adaptive response to hyperglycemia gone awry? Trans Am Clin Climatol Assoc 117: 341351.
  • Fadini GP, Boscaro E, de Kreutzenberg S, Agostini C, Seeger F, Dimmeler S, Zeiher A, Tiengo A, Avogaro A. 2010. Time course and mechanisms of circulating progenitor cell reduction in the natural history of type 2 diabetes. Diabetes Care 33: 10971102.
  • Fujimiya M, Kojima H, Ichinose M, Arai R, Kimura H, Kashiwagi A, Chan L. 2007. Fusion of proinsulin-producing bone marrow-derived cells with hepatocytes in diabetes. Proc Natl Acad Sci USA 104: 40304035.
  • Jin P, Zhang X, Wu Y, Li L, Yin Q, Zheng L, Zhang H, Sun C. 2010. Streptozotocin-induced diabetic rat-derived bone marrow mesenchymal stem cells have impaired abilities in proliferation, paracrine, antiapoptosis, and myogenic differentiation. Transplant Proc 42: 27452752.
  • Kasahara T, Imai S, Kojima H, Katagi M, Kimura H, Chan L, Matsusue Y. 2010. Malfunction of bone marrow-derived osteoclasts and the delay of bone fracture healing in diabetic mice. Bone 47: 617625.
  • Kojima H, Fujimiya M, Matsumura K, Nakahara T, Hara M, Chan L. 2004. Extrapancreatic insulin-producing cells in multiple organs in diabetes. Proc Natl Acad Sci USA 101: 24582463.
  • Kojima H, Fujimiya M, Terashima T, Kimura H, Chan L. 2006. Extrapancreatic proinsulin/insulin-expressing cells in diabetes mellitus: is history repeating itself? Endocr J 53: 715722.
  • Orlandi A, Chavakis E, Seeger F, Tjwa M, Zeiher AM, Dimmeler S. 2010. Long-term diabetes impairs repopulation of hematopoietic progenitor cells and dysregulates the cytokine expression in the bone marrow microenvironment in mice. Basic Res Cardiol 105: 703712.
  • Phadnis SM, Ghaskadbi SM, Hardikar AA, Bhonde RR. 2009. Mesenchymal stem cells derived from bone marrow of diabetic patients portrait unique markers influenced by the diabetic microenvironment. Rev Diabet Stud 6: 260270.
  • Rosen CJ, Ackert-Bicknell C, Rodriguez JP, Pino AM. 2009. Marrow fat and the bone microenvironment: developmental, functional, and pathological implications. Crit Rev Eukaryot Gene Expr 19: 109124.
  • Tepper OM, Carr J, Allen RJ, Jr., Chang CC, Lin CD, Tanaka R, Gupta SM, Levine JP, Saadeh PB, Warren SM. 2010. Decreased circulating progenitor cell number and failed mechanisms of stromal cell-derived factor-1alpha mediated bone marrow mobilization impair diabetic tissue repair. Diabetes 59: 19741983.
  • Terashima T, Kojima H, Fujimiya M, Matsumura K, Oi J, Hara M, Kashiwagi A, Kimura H, Yasuda H, Chan L. 2005. The fusion of bone-marrow-derived proinsulin-expressing cells with nerve cells underlies diabetic neuropathy. Proc Natl Acad Sci USA 102: 1252512530.
  • Yamashita T, Fujimiya M, Nagaishi K, Ataka K, Tanaka M, Yoshida H, Tsuchihashi K, Shimamoto K, Miura T. Fusion of bone marrow-derived cells with renal tubules contributes to renal dysfunction in diabetic nephropathy. FASEB J, in press.