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LITERATURE CITED

  • Bravou V, Klironomos G, Papadaki E, Taraviras S, Varakis J. 2006. ILK over-expression in human colon cancer progression correlates with activation of beta-catenin, down-regulation of E-cadherin and activation of the Akt-FKHR pathway. J Pathol 208:9199.
  • Chen N, Karantza V. 2011. Autophagy as a therapeutic target in cancer. Cancer Biol Ther 11:157168.
  • DeBerardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB. 2008. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab 7:1120.
  • Ding ZB, Hui B, Shi YH, Zhou J, Peng YF, Gu CY, Yang H, Shi GM, Ke AW, Wang XY, Song K, Dai Z, Shen YH, Fan J. 2011. Autophagy activation in hepatocellular carcinoma contributes to the tolerance of oxaliplatin via reactive oxygen species modulation. Clin Cancer Res 17:62296238.
  • Eskelinen EL, Saftig P. 2009. Autophagy: a lysosomal degradation pathway with a central role in health and disease. Biochim Biophys Acta 1793:664673.
  • Fujii S, Mitsunaga S, Yamazaki M, Hasebe T, Ishii G, Kojima M, Kinoshita T, Ueno T, Esumi H, Ochiai A. 2008. Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome. Cancer Sci 99:18131819.
  • Giatromanolaki A, Koukourakis MI, Harris AL, Polychronidis A, Gatter KC, Sivridis E. 2010. Prognostic relevance of light chain 3 (LC3A) autophagy patterns in colorectal adenocarcinomas. J Clin Pathol 63:867872.
  • Guo JY, Chen HY, Mathew R, Fan J, Strohecker AM, Karsli-Uzunbas G, Kamphorst JJ, Chen G, Lemons JM, Karantza V, Coller HA, Dipaola RS, Gelinas C, Rabinowitz JD, White E. 2011. Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes Dev 25:460470.
  • Guo XL, Li D, Sun K, Wang J, Liu Y, Song JR, Zhao QD, Zhang SS, Deng WJ, Zhao X, Wu MC, Wei LX. 2013. Inhibition of autophagy enhances anticancer effects of bevacizumab in hepatocarcinoma. J Mol Med (Berl) 91:473483.
  • He H, Dang Y, Dai F, Guo Z, Wu J, She X, Pei Y, Chen Y, Ling W, Wu C, Zhao S, Liu JO, Yu L. 2003. Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B. J Biol Chem 278:2927829287.
  • Jensen EC. 2012. The basics of western blotting. Anat Rec (Hoboken) 295:369371.
  • Karpathiou G, Sivridis E, Koukourakis MI, Mikroulis D, Bouros D, Froudarakis ME, Giatromanolaki A. 2011. Light-chain 3A autophagic activity and prognostic significance in non-small cell lung carcinomas. Chest 140:127134.
  • Kimmelman AC. 2011. The dynamic nature of autophagy in cancer. Genes Dev 25:19992010.
  • Lauren P. 1965. The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand 64:3149.
  • Liu EY, Ryan KM. 2012. Autophagy and cancer—issues we need to digest. J Cell Sci 125:23492358.
  • Marino G, Lopez-Otin C. 2004. Autophagy: molecular mechanisms, physiological functions and relevance in human pathology. Cell Mol Life Sci 61:14391454.
  • Miracco C, Cosci E, Oliveri G, Luzi P, Pacenti L, Monciatti I, Mannucci S, De Nisi MC, Toscano M, Malagnino V, Falzarano SM, Pirtoli L, Tosi P. 2007. Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours. Int J Oncol 30:429436.
  • Mizushima N. 2004. Methods for monitoring autophagy. Int J Biochem Cell Biol 36:24912502.
  • Mizushima N, Ohsumi Y, Yoshimori T. 2002. Autophagosome formation in mammalian cells. Cell Struct Funct 27:421429.
  • Mizushima N, Yoshimori T, Levine B. 2010. Methods in mammalian autophagy research. Cell 140:313326.
  • O'Donovan TR, O'Sullivan GC, McKenna SL. 2011. Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics. Autophagy 7:509524.
  • Pan X, Zhou T, Tai YH, Wang C, Zhao J, Cao Y, Chen Y, Zhang PJ, Yu M, Zhen C, Mu R, Bai ZF, Li HY, Li AL, Liang B, Jian Z, Zhang WN, Man JH, Gao YF, Gong WL, Wei LX, Zhang XM. 2011. Elevated expression of CUEDC2 protein confers endocrine resistance in breast cancer. Nat Med 17:708714.
  • Qiu MZ, Cai MY, Zhang DS, Wang ZQ, Wang DS, Li YH, Xu RH. 2013. Clinicopathological characteristics and prognostic analysis of Lauren classification in gastric adenocarcinoma in China. J Transl Med 11:58.
  • Sato K, Tsuchihara K, Fujii S, Sugiyama M, Goya T, Atomi Y, Ueno T, Ochiai A, Esumi H. 2007. Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. Cancer Res 67:96779684.
  • Sivridis E, Giatromanolaki A, Karpathiou G, Karpouzis A, Kouskoukis C, Koukourakis MI. 2011. LC3A-positive “stone-like” structures in cutaneous squamous cell carcinomas. Am J Dermatopathol 33:285290.
  • Sivridis E, Giatromanolaki A, Zois C, Koukourakis MI. 2010a. The “stone-like” pattern of autophagy in human epithelial tumors and tumor-like lesions: an approach to the clinical outcome. Autophagy 6:830833.
  • Sivridis E, Koukourakis MI, Mendrinos SE, Touloupidis S, Giatromanolaki A. 2013. Patterns of autophagy in urothelial cell carcinomas-the significance of “stone-like” structures (SLS) in transurethral resection biopsies. Urol Oncol 31:12541260.
  • Sivridis E, Koukourakis MI, Zois CE, Ledaki I, Ferguson DJ, Harris AL, Gatter KC, Giatromanolaki A. 2010b. LC3A-positive light microscopy detected patterns of autophagy and prognosis in operable breast carcinomas. Am J Pathol 176:24772489.
  • Spowart JE, Townsend KN, Huwait H, Eshragh S, West NR, Ries JN, Kalloger S, Anglesio M, Gorski SM, Watson PH, Gilks CB, Huntsman DG, Lum JJ. 2012. The autophagy protein LC3A correlates with hypoxia and is a prognostic marker of patient survival in clear cell ovarian cancer. J Pathol 228:437447.
  • Sun T, Zhao N, Zhao XL, Gu Q, Zhang SW, Che N, Wang XH, Du J, Liu YX, Sun BC. 2010. Expression and functional significance of Twist1 in hepatocellular carcinoma: its role in vasculogenic mimicry. Hepatology 51:545556.
  • White E, DiPaola RS. 2009. The double-edged sword of autophagy modulation in cancer. Clin Cancer Res 15:53085316.
  • Wu WK, Cho CH, Lee CW, Wu YC, Yu L, Li ZJ, Wong CC, Li HT, Zhang L, Ren SX, Che CT, Wu K, Fan D, Yu J, Sung JJ. 2010. Macroautophagy and ERK phosphorylation counteract the antiproliferative effect of proteasome inhibitor in gastric cancer cells. Autophagy 6:228238.
  • Xi SY, Lu JB, Chen JW, Cao Y, Luo RZ, Wu QL, Cai MY. 2013. The “stone-like” pattern of LC3A expression and its clinicopathologic significance in hepatocellular carcinoma. Biochem Biophys Res Commun 431:760766.
  • Yang S, Kimmelman AC. 2011. A critical role for autophagy in pancreatic cancer. Autophagy 7:912913.
  • Yang S, Wang X, Contino G, Liesa M, Sahin E, Ying H, Bause A, Li Y, Stommel JM, Dell'Antonio G, Mautner J, Tonon G, Haigis M, Shirihai OS, Doglioni C, Bardeesy N, Kimmelman AC. 2011. Pancreatic cancers require autophagy for tumor growth. Genes Dev 25:717729.
  • Yoshioka A, Miyata H, Doki Y, Yamasaki M, Sohma I, Gotoh K, Takiguchi S, Fujiwara Y, Uchiyama Y, Monden M. 2008. LC3, an autophagosome marker, is highly expressed in gastrointestinal cancers. Int J Oncol 33:461468.
  • Zuo Q, Huang H, Shi M, Zhang F, Sun J, Bin J, Liao Y, Liao W. 2012. Multivariate analysis of several molecular markers and clinicopathological features in postoperative prognosis of hepatocellular carcinoma. Anat Rec (Hoboken) 295:423431.