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Regenerative medicine is the basis of 21st-century biomedicine. A special 2-day AAA mini-meeting on this topic will highlight the novel role of stem cells in tissue turnover and regeneration, identify important basic science issues, and demonstrate how understanding basic science principles can be translated into novel therapeutic and diagnostic modalities.

The program, chaired by Vladimir Mironov (Medical University of South Carolina), features its own poster session, chaired by Jay Potts (University of South Carolina), and four symposia, described below.

Stem Cells for Regenerative Medicine

  1. Top of page
  2. Stem Cells for Regenerative Medicine
  3. Biomimetic Matrices for Regenerative Medicine
  4. Endothelial-Mesenchymal Transformation in Cardiovascular Regenerative Medicine
  5. Tissue Engineering Technologies for Regenerative Medicine
  6. WHAT'S A MINI-MEETING?

Regenerative medicine could be defined as applied stem cell, regenerative, and developmental biology. The stem cell is the keystone of the ongoing regenerative medicine revolution. Both embryonic and adult stem cells demonstrate potential for effective applications in regenerative medicine. However, effective clinical translation must be based on systematic studies of stem cell biology, tissue turnover, and regeneration, as well as on understanding the mechanisms of integration of implanted cells into preexisting tissues and organs. This session focuses on different types of stem cells and their application in regenerative medicine. Chair:Marc Hedrick (Macropore Biosurgery Inc).

Biomimetic Matrices for Regenerative Medicine

  1. Top of page
  2. Stem Cells for Regenerative Medicine
  3. Biomimetic Matrices for Regenerative Medicine
  4. Endothelial-Mesenchymal Transformation in Cardiovascular Regenerative Medicine
  5. Tissue Engineering Technologies for Regenerative Medicine
  6. WHAT'S A MINI-MEETING?

Regenerative medicine is impossible without effective cell delivery. It is obvious that designing an optimal microenvironment is critical for successful cell therapy and cell transplantation. Injectable tissue engineering is based on employing intelligent hydrogels or functional biomimetic matrices. Functional matrices from modified natural polymers are closely mimicking natural components of extracellular matrix and even have some additional advantages because they are designed as stimuli-sensitive or smart hydrogels. This session focuses on the application of biomimetic matrices in regenerative medicine. Chair:Kevin Healy (University of California at Berkeley).

Endothelial-Mesenchymal Transformation in Cardiovascular Regenerative Medicine

  1. Top of page
  2. Stem Cells for Regenerative Medicine
  3. Biomimetic Matrices for Regenerative Medicine
  4. Endothelial-Mesenchymal Transformation in Cardiovascular Regenerative Medicine
  5. Tissue Engineering Technologies for Regenerative Medicine
  6. WHAT'S A MINI-MEETING?

Endothelial cell and tissue biology is a fundamental basic research field that is critically important for progress in cardiovascular regenerative medicine. Angiogenesis and vasculogenesis are the current focus of research on endothelial cell and tissue biology. However, endothelial cells produce new blood vessel and proliferate in response on signals or injury. Endothelial-mesenchymal transformation and associated fibrosis are becoming recognized as potential pathogenetic mechanism for many fibroproliferative diseases. This session focuses on the application of endothelial mesenchymal transformation to emerging field of cardiovascular regenerative medicine. Chair:Joyce Bishoff (Harvard University).

Tissue Engineering Technologies for Regenerative Medicine

  1. Top of page
  2. Stem Cells for Regenerative Medicine
  3. Biomimetic Matrices for Regenerative Medicine
  4. Endothelial-Mesenchymal Transformation in Cardiovascular Regenerative Medicine
  5. Tissue Engineering Technologies for Regenerative Medicine
  6. WHAT'S A MINI-MEETING?

Self-assembly is a fundamental biological process at all scales. Exploring principles of directed and even self-directed tissue self-assembly opens a unique opportunity for regenerative medicine and tissue engineering. Many soft tissues and especially cell aggregates are not solid but rather viscoelastic fluid-like structures and they can flow and fuse. This session focuses on new emerging tissue engineering technologies for regenerative medicine based on the principles of tissue self-assembly. Chair:Vladimir Mironov (Medical University of South Carolina).

WHAT'S A MINI-MEETING?

  1. Top of page
  2. Stem Cells for Regenerative Medicine
  3. Biomimetic Matrices for Regenerative Medicine
  4. Endothelial-Mesenchymal Transformation in Cardiovascular Regenerative Medicine
  5. Tissue Engineering Technologies for Regenerative Medicine
  6. WHAT'S A MINI-MEETING?

AAA initiated its successful mini-meeting format in 2004. A mini-meeting is a 2-day event during the AAA Annual Meeting at Experimental Biology that addresses a timely issue of sufficient breadth to attract registrants from several FASEB societies. The program includes four 2-hour symposia, each with four invitedspeakers, and a concurrent poster session posted for both days of the mini-meeting.

AAA provides $10,000 to help defray a portion of travel costs for invited speakers and covers the registration and abstract fees for eight of the invited speakers. All other expenses must be supported by outside funding solicited by the organizer or covered by individual speakers.

If you'd like to organize your own mini-meeting for EB 2007 or future years, just go to the AAA Website (www.anatomy.org), click on “Meeting/Proposal Form,” review the guidelines, and submit a proposal. All proposals will be evaluated by the AAA Annual Meeting Program Committee on April 5.

Take advantage of this unique opportunity to create new synergy in your own area of research!