Sites of collagenase cleavage and denaturation of type II collagen in aging and osteoarthritic articular cartilage and their relationship to the distribution of matrix metalloproteinase 1 and matrix metalloproteinase 13
Version of Record online: 9 AUG 2002
Copyright © 2002 by the American College of Rheumatology
Arthritis & Rheumatism
Volume 46, Issue 8, pages 2087–2094, August 2002
How to Cite
Wu, W., Billinghurst, R. C., Pidoux, I., Antoniou, J., Zukor, D., Tanzer, M. and Poole, A. R. (2002), Sites of collagenase cleavage and denaturation of type II collagen in aging and osteoarthritic articular cartilage and their relationship to the distribution of matrix metalloproteinase 1 and matrix metalloproteinase 13. Arthritis & Rheumatism, 46: 2087–2094. doi: 10.1002/art.10428
- Issue online: 9 AUG 2002
- Version of Record online: 9 AUG 2002
- Manuscript Accepted: 16 APR 2002
- Manuscript Received: 18 OCT 2001
- Shriners Hospitals for Children
- National Institute on Aging
- Canadian Institute of Health Research
- Canadian Arthritis Network
- Fonds de la Recherche et Santé du Quebec
- 1Mechanical properties of articular cartilage. In: FreemanMAR, editor. Adult articular cartilage. 2nd ed. Turnbridge Wells (UK): Pitman Medical; 1979. p. 333–414..
- 5The tensile properties of the cartilage of human femoral condyles related to the content of collagen and glycosaminoglycans. Biochem Biophys Acta 1973; 297: 465–72., , , .
- 7Selective enhancement of collagenase-mediated cleavage of resident type II collagen in cultured osteoarthritic cartilage and arrest with a synthetic inhibitor that spares collagenase 1 (matrix metalloproteinase 1). Arthritis Rheum 2000; 43: 673–82., , , , , , et al.
- 8Comparison of the degradation of type II collagen and proteoglycan in nasal and articular cartilages induced by interleukin-1 and the selective inhibition of type II collagen cleavage by collagenase. Arthritis Rheum 2000; 43: 664–72., , , , , , et al.
- 12Cartilage in health and disease. In: KoopmanWJ, editor. Arthritis and allied conditions. 14th ed. Philadelphia (PA): Lippincott, Williams & Wilkins; 2001. p. 226–84..
- 13Etiopathogenesis of osteoarthritis. In: MoskowitzRW, HowellDS, AltmanRD, BuckwalterJA, GoldbergVM, editors. Osteoarthritis diagnosis and management. 3rd ed. Philadelphia (PA): WB Saunders; 2001. p. 29–47., .
- 14Collagenase-3 (matrix metalloproteinase 13) is preferentially localized in the deep layer of human arthritic cartilage in situ: in vitro mimicking effect by transforming growth factor β. Arthritis Rheum 1997; 40: 1653–61., , , , .
- 18Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Development of criteria for the classification and reporting of osteoarthritis: classification of osteoarthritis of the knee. Arthritis Rheum 1986; 29: 1039–49., , , , , , et al, and the