See acknowledgments for members of the LUMINA Study Group
Systemic lupus erythematosus in three ethnic groups. XI. Sources of discrepancy in perception of disease activity: A comparison of physician and patient visual analog scale scores†
Article first published online: 12 AUG 2002
Copyright © 2002 by the American College of Rheumatology
Arthritis Care & Research
Volume 47, Issue 4, pages 408–413, 15 August 2002
How to Cite
Alarcón, G. S., McGwin, G., Brooks, K., Roseman, J. M., Fessler, B. J., Sanchez, M. L., Bastian, H. M., Friedman, A. W., Baethge, B. A., Reveille, J. D. and LUMINA STUDY GROUP (2002), Systemic lupus erythematosus in three ethnic groups. XI. Sources of discrepancy in perception of disease activity: A comparison of physician and patient visual analog scale scores. Arthritis & Rheumatism, 47: 408–413. doi: 10.1002/art.10512
- Issue published online: 12 AUG 2002
- Article first published online: 12 AUG 2002
- Manuscript Accepted: 24 OCT 2001
- Manuscript Received: 1 JUN 2001
- NIH, Institute of Arthritis and Musculoskeletal and Skin Diseases. Grant Number: R01-AR-42503
- General Clinical Center Research Grants. Grant Numbers: M01-RR-02558, M01-RR-00073, M01-RR-00032
- Systemic lupus erythematosus;
- Disease activity;
- Visual analog scale;
To compare patient's and physician's assessment of disease activity in a multiethnic (Hispanic, African American, and Caucasian) cohort of systemic lupus erythematosus (SLE) patients.
Three hundred patients with SLE from the LUMINA (Lupus in Minority populations: Nature versus nurture) cohort were included. Disease activity was assessed with the Systemic Lupus Activity Measure (SLAM); patients and physicians assessed disease activity using a 10-cm anchored visual analog scale (VAS). The difference between VAS scores was termed discrepancy (>1 cm was considered a priori clinically relevant). Selected sociodemographic, clinical, behavioral, and psychological variables were examined in relation to discrepancy in univariable and multivariable models adjusting for the physician global VAS score in order to eliminate ceiling and floor effects.
A discrepancy was exhibited by 58% of the patients. Abnormal laboratory findings were negatively associated with discrepancy, and poor self-perceived functioning and joint involvement were positively associated with discrepancy. Ethnicity did not account for discrepant perception of disease activity.
Patients and physicians rate disease activity in SLE differently. Physicians appear to place more emphasis on laboratory features while patients place more emphasis on function.