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Dehydroepiandrosterone treatment of women with mild-to-moderate systemic lupus erythematosus: A multicenter randomized, double-blind, placebo-controlled trial
Article first published online: 8 NOV 2002
DOI: 10.1002/art.10615
Copyright © 2002 by the American College of Rheumatology
1529-0131/asset/cover.gif?v=1&s=104d5c2bb8ef72deba26790b855af7ab80697a0e "Arthritis & Rheumatism")
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How to Cite
Chang, D.-M., Lan, J.-L., Lin, H.-Y. and Luo, S.-F. (2002), Dehydroepiandrosterone treatment of women with mild-to-moderate systemic lupus erythematosus: A multicenter randomized, double-blind, placebo-controlled trial. Arthritis & Rheumatism, 46: 2924–2927. doi: 10.1002/art.10615
Publication History
- Issue published online: 8 NOV 2002
- Article first published online: 8 NOV 2002
- Manuscript Accepted: 26 JUL 2002
- Manuscript Received: 6 FEB 2002
Funded by
- Genelabs Biotechnology Company, Ltd.
- National Science Council. Grant Number: NSC90-2314-B-016-069
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- 1, , , , , , , , , , , , Dehydroepiandrosterone (DHEA) improves pulmonary hypertension in chronic obstructive pulmonary disease (COPD): A pilot study, Annales d'Endocrinologie, 2012, 73, 1, 20
- 2, , , , Dehydroepiandrosterone (DHEA)—A Precursor Steroid or an Active Hormone in Human Physiology (CME), The Journal of Sexual Medicine, 2011, 8, 11Direct Link:
- 3, , Measuring outcomes in systemic lupus erythematosus clinical trials, Expert Review of Pharmacoeconomics & Outcomes Research, 2011, 11, 4, 455
- 4
- 5
- 6, , , Dehydroepiandrosterone as a regulator of immune cell function, The Journal of Steroid Biochemistry and Molecular Biology, 2010, 120, 2-3, 127
- 7, , , , , , , Late onset lupus nephritis: analysis of clinical manifestations and renal pathological features in Chinese patients, Rheumatology International, 2010, 31, 12, 1625
- 8, , , New insights into the protective effects of DHEA1), Hormone Molecular Biology and Clinical Investigation, 2010, 4, 1, 489
- 9, , , , , Oral contraceptives and risk of systemic lupus erythematosus, International Journal of Clinical Rheumatology, 2010, 5, 2, 169
- 10, , , , , , , Pathogenesis of human systemic lupus erythematosus: recent advances, Trends in Molecular Medicine, 2010, 16, 2, 47
- 11
- 12
- 13, , Dehydroepiandrosterone in systemic lupus erythematosus, Current Rheumatology Reports, 2008, 10, 4, 286
- 14, , Elevation of fasting insulin and its association with cardiovascular disease risk in women with systemic lupus erythematosus, Rheumatology International, 2008, 29, 7, 735
- 15, , Learning from past mistakes: assessing trial quality, power and eligibility in non-renal systemic lupus erythematosus randomized controlled trials, Rheumatology, 2008, 47, 9, 1367
- 16
- 17, , , The physiological and pharmacological basis for the ergogenic effects of androgens in elite sports, Asian Journal of Andrology, 2008, 10, 3Direct Link:
- 18
- 19
- 20, , , , , , , A dehidroepiandroszteron és dehidroepiandroszteron-szulfát jelentôsége különböző kórállapotokban, Orvosi Hetilap, 2007, 148, 14, 651
- 21, , , Lupus nephritis remission, albeit with positive anti-doping test, Joint Bone Spine, 2007, 74, 1, 96
- 22, Management of systemic lupus erythematosus in Chinese patients, Expert Review of Clinical Immunology, 2007, 3, 6, 925
- 23, , , Might DHEA be Considered a Beneficial Replacement Therapy in the Elderly?, Drugs & Aging, 2007, 24, 3, 173
- 24, , , Rémission d'une néphrite lupique, malgré un test antidopage positif, Revue du Rhumatisme, 2007, 74, 1, 105
- 25, , , , Reproductive and menopausal factors and risk of systemic lupus erythematosus in women, Arthritis & Rheumatism, 2007, 56, 4Direct Link:
- 26, , Systemic lupus erythematosus: modern strategies for management – a moving target, Best Practice & Research Clinical Rheumatology, 2007, 21, 6, 971
- 27, , , , A positive correlation between homocysteine and brachial–ankle pulse wave velocity in patients with systemic lupus erythematosus, Clinical Rheumatology, 2006, 25, 3, 285
- 28, Dehydroepiandrosterone replacement therapy, Current Opinion in Endocrinology and Diabetes, 2006, 13, 3, 291
- 29, , , Differential effect of DHEA on mitogen-induced proliferation of T and B lymphocytes, The Journal of Steroid Biochemistry and Molecular Biology, 2006, 99, 2-3, 115
- 30, , , , Effect of dehydroepiandrosterone on cartilage and synovium of knee joints with osteoarthritis in rabbits, Rheumatology International, 2006, 27, 1, 79
- 31, Emerging drug therapies for systemic lupus erythematosus, Expert Opinion on Emerging Drugs, 2006, 11, 4, 597
- 32, , , , , , , , , Endocrine effects of oral dehydroepiandrosterone in men with HIV infection: a prospective, randomized, double-blind, placebo-controlled trial, Metabolism, 2006, 55, 7, 858
- 33, , , Enhanced oxidative status but not corresponding elevated antioxidative status by anticardiolipin antibody and disease activity in patients with systemic lupus erythematosus, Rheumatology International, 2006, 27, 5, 453
- 34, , , Lupus erythematosus: systemic and cutaneous manifestations, Clinics in Dermatology, 2006, 24, 5, 348
- 35, , Systemic lupus erythematosus: clinical manifestations, treatment and economics, Expert Review of Pharmacoeconomics & Outcomes Research, 2006, 6, 5, 563
- You have free access to this content36, Therapeutic advances in systemic lupus erythematosus, APLAR Journal of Rheumatology, 2006, 9, 1Direct Link:
- 37
- 38
- 39, , , , , , , , Dehydroepiandrosterone negatively regulates the p38 mitogen-activated protein kinase pathway by a novel mitogen-activated protein kinase phosphatase, Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 2005, 1728, 1-2, 84
- 40, , , , , , Effects of dehydroepiandrosterone supplement on health-related quality of life in glucocorticoid treated female patients with systemic lupus erythematosus, Autoimmunity, 2005, 38, 7, 531
- 41, Emergence of targeted immune therapies for systemic lupus, Expert Opinion on Emerging Drugs, 2005, 10, 1, 53
- 42, , Newer Therapeutic Approaches for Systemic Lupus Erythematosus, Rheumatic Disease Clinics of North America, 2005, 31, 2, 315
- 43, , , Novel approaches to therapy for systemic lupus erythematosus: update 2005, Expert Review of Clinical Immunology, 2005, 1, 2, 223
- 44, , The Use of Dehydroepiandrosterone Therapy in Clinical Practice, Treatments in Endocrinology, 2005, 4, 2, 95
- 45, Traitements hormonaux et protection ovarienne au cours du lupus systémique, Revue du Rhumatisme, 2005, 72, 6, 546
- 46
- 47, , , , , , 17α-Hydroxylase/C17-20 Lyase Cytochrome P450 mRNA Expressions and Enzyme Activities during the Development of Arthritis in Collagen-Induced Arthritis Mice, Biological & Pharmaceutical Bulletin, 2004, 27, 10, 1663
- 48, , , Challenges in bringing the bench to bedside in drug development for sle, Nature Reviews Drug Discovery, 2004, 3, 12, 1036
- 49, , , , , Clinical evaluation of insulin resistance and ?-cell function by the homeostasis model assessment in patients with systemic lupus erythematosus, Clinical Rheumatology, 2004, 23, 5, 416
- 50, Dehydroepiandrosterone and ageing, Best Practice & Research Clinical Endocrinology & Metabolism, 2004, 18, 3, 363
- 51, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Effects of prasterone on disease activity and symptoms in women with active systemic lupus erythematosus, Arthritis & Rheumatism, 2004, 50, 9Direct Link:
- 52
- 53, , Hormones and immune function: implications of aging, Aging Cell, 2004, 3, 4Direct Link:
- 54
- 55, , Lupus nephritis: a review of the current pharmacological treatments, Expert Opinion on Pharmacotherapy, 2004, 5, 11, 2263
- 56, , , , , , Participants Receiving Dehydroepiandrosterone During Treatment for Cocaine Dependence Show High Rates of Cocaine Use in a Placebo-Controlled Pilot Study., Experimental and Clinical Psychopharmacology, 2004, 12, 2, 126
- 57, , , Pathogenesis of SLE: implications for rational therapy, Drug Discovery Today: Disease Mechanisms, 2004, 1, 3, 303
- 58, Pediatric lupus versus adult lupus role of the laboratory, Clinical and Applied Immunology Reviews, 2004, 4, 5, 333
- 59, , , , , , , , , , , Pilot clinical trial of dehydroepiandrosterone (DHEA) versus placebo for Sjögren's syndrome, Arthritis Care & Research, 2004, 51, 4Direct Link:
- 60, , Systemic lupus erythematosus trials: successes and issues, Current Opinion in Rheumatology, 2004, 16, 5, 499
- 61, , , , , , The effect of dehydroepiandrosterone on lumbar spine bone mineral density in patients with quiescent systemic lupus erythematosus, Arthritis & Rheumatism, 2004, 50, 11Direct Link:
- 62, Dehydroepiandrosterone, a sex steroid metabolite in development for systemic lupus erythematosus, Expert Opinion on Investigational Drugs, 2003, 12, 6, 1017
- 63, , Dehydroepiandrosterone: Is There a Role for Replacement?, Mayo Clinic Proceedings, 2003, 78, 10, 1257
- 64, , , , , , Patients with refractory Crohn's disease or ulcerative colitis respond to dehydroepiandrosterone: a pilot study, Alimentary Pharmacology & Therapeutics, 2003, 17, 3Direct Link:
- 65, , Pharmacology And Therapeutic Effects of Dehydroepiandrosterone In Older Subjects, Drugs & Aging, 2003, 20, 13, 949
- 66, , Sex hormones and systemic lupus erythematosus: Review and meta-analysis, Arthritis & Rheumatism, 2003, 48, 8Direct Link:
- 67, The Role of Plasmapheresis in the Treatment of Severe Central Nervous System Neuropsychiatric Systemic Lupus Erythematosus, Therapeutic Apheresis and Dialysis, 2003, 7, 2Direct Link:
- 68, , , , , Dehydroepiandrosterone for systemic lupus erythematosus, The Cochrane Library,Direct Link: