Research Article

You have full text access to this OnlineOpen article

Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis

  1. Solbritt Rantapää-Dahlqvist1,*,
  2. Ben A. W. de Jong2,
  3. Ewa Berglin1,
  4. Göran Hallmans1,
  5. Göran Wadell1,
  6. Hans Stenlund1,
  7. Ulf Sundin3,
  8. Walther J. van Venrooij2

Article first published online: 7 OCT 2003

DOI: 10.1002/art.11223

Issue

Arthritis & Rheumatism

Arthritis & Rheumatism

Volume 48, Issue 10, pages 2741–2749, October 2003

Additional Information

How to Cite

Rantapää-Dahlqvist, S., de Jong, B. A. W., Berglin, E., Hallmans, G., Wadell, G., Stenlund, H., Sundin, U. and van Venrooij, W. J. (2003), Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis. Arthritis & Rheumatism, 48: 2741–2749. doi: 10.1002/art.11223

Author Information

  1. 1

    Umeå Universitet, Umea, Sweden

  2. 2

    University of Nijmegen, Nijmegen, The Netherlands

  3. 3

    Huddinge University Hospital, Stockholm, Sweden

*Department of Public Health and Clinical Medicine, Rheumatology, University Hospital, Umea 901 85, Sweden

Publication History

  1. Issue published online: 7 OCT 2003
  2. Article first published online: 7 OCT 2003
  3. Manuscript Accepted: 9 MAY 2003
  4. Manuscript Received: 9 DEC 2002

Funded by

  • King Gustaf V's 80-Year Fund
  • Swedish Rheumatism Association
  • Medical Faculty of Umea University, Umea, Sweden
  • The Netherlands Organization for Scientific Research in the Medical Sciences
  • Dutch League Against Rheumatism. Grant Number: NWO-MW grant 940-35-037
  • Council for Chemical Sciences
  • The Netherlands Technology Foundation. Grant Number: STW grant 349-5077

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article (HTML) Get PDF (95K)

REFERENCES

  • 1
    Van Venrooij WJ, Pruijn GJM. Citrullination: a small change for a protein with great consequences for rheumatoid arthritis. Arthritis Res 2000; 2: 249–51.
  • 2
    Schellekens GA, Visser H, de Jong BAW, van den Hoogen FHJ, Hazes JMW, Breedveld FC, van Venrooij WJ. The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide. Arthritis Rheum 2000; 43: 155–63.
    Direct Link:
  • 3
    Visser H, le Cessie S, Vos K, Breedveld FC, Hazes JMW. How to diagnose rheumatoid arthritis early: a prediction model for persistent (erosive) arthritis. Arthritis Rheum 2002; 46: 357–65.
    Direct Link:
  • 4
    Aho K, Palosuo T, Raunio V, Puska P, Aromaa A, Salonen JT. When does rheumatoid disease start? Arthritis Rheum 1985; 28: 485–9.
    Direct Link:
  • 5
    Aho K, von Essen R, Kurki P, Palosuo T, Heliövaara M. Antikeratin antibody and antiperinuclear factor as markers for subclinical rheumatoid disease process. J Rheumatol 1993; 20: 1278–81.
  • 6
    Aho K, Palosuo T, Heliövaara M, Knekt P, Alha P, von Essen R. Antifilaggrin antibodies within “normal” range predict rheumatoid arthritis in a linear fashion. J Rheumatol 2000; 27: 2743–6.
  • 7
    Jonsson T, Thorsteinsson J, Valdimarsson H. Elevation of only one rheumatoid factor isotype is not associated with increased prevalence of rheumatoid arthritis: a population based study. Scand J Rheumatol 2000; 29: 190–1.
  • 8
    Heliövaara M, Aho K, Aromaa A, Knekt P, Reunanene A. Smoking and risk of rheumatoid arthritis. J Rheumatol 1993; 20: 1830–5.
  • 9
    Jonsson T, Thorsteinsson J, Valdimarsson H.. Does smoking stimulate rheumatoid factor production in non-rheumatic individuals. APMIS 1998; 106: 970–4.
    Direct Link:
  • 10
    Van Doornum S, McColl G, Wicks IP. Accelerated atherosclerosis: an extraarticular feature of rheumatoid arthritis? Arthritis Rheum 2002; 46: 862–73.
    Direct Link:
  • 11
    Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 315–24.
    Direct Link:
  • 12
    GahlingerPM, AbramsonJH, editors. Computer programs for epidemiologic analysis. Makapuu Medical Press: Honolulu; 1997.
  • 13
    Eberhardt KB, Svensson B, Truedsson L, Wollheim FA. The occurrence of rheumatoid factor isotypes in early definite rheumatoid arthritis—no relationship with erosions or disease activity. J Rheumatol 1988; 15: 1070–4.
  • 14
    Kroot E-JJA, de Jong BAW, van Leeuwen MA, Swinkels H, van den Hoogen FHJ, van 't Hof M, et al. The prognostic value of anti–cyclic citrullinated peptide antibody in patients with recent-onset rheumatoid arthritis. Arthritis Rheum 2000; 43: 1831–5.
    Direct Link:
  • 15
    Jonsson T, Thorsteinsson J, Kolbeinsson A, Jonasdottir E, Sigfusson N, Valdimarsson H. Population study of the importance of rheumatoid factor isotypes in adults. Ann Rheum Dis 1992; 51: 863–8.
  • 16
    Quinn MA, Conaghan PG, Emery P. The therapeutic approach of early intervention for rheumatoid arthritis: what is the evidence? Rheumatology (Oxford) 2001; 40: 1211–20.
  • 17
    Möttönen T, Hannonen P, Korpela M, Nissilä M, Kautiainen H, Ilonen J, et al. Delay to institution of therapy and induction of remission using single-drug or combination–disease-modifying antirheumatic drug therapy in early rheumatoid arthritis. Arthritis Rheum 2002; 46: 894–8.
    Direct Link:
  • 18
    O'Dell JR. Treating rheumatoid arthritis early: a window of opportunity? Arthritis Rheum 2002; 46: 283–5.
    Direct Link:
  • 19
    Kopans DB, Moore RH, McCarthy KA, Hall DA, Hulka CA, Whitman GJ, et al. Positive predictive value of breast biopsy performed as a result of mammography: there is no abrupt change at age 50 years. Radiology 1996; 200: 357–60.
  • 20
    McMurray RW. Estrogen, prolactin and autoimmunity: actions and interactions. Int Immunopharmacol 2001; 1: 995–1008.
  • 21
    Barrett JH, Brennan P, Fiddler M, Silman AJ. Does rheumatoid arthritis remit during pregnancy and relapse postpartum? Results from a nationwide study in the United Kingdom performed prospectively from late pregnancy. Arthritis Rheum 1999; 42: 1219–27.
    Direct Link:
  • 22
    Rook GA, Steele J, Brenley R, Whyte A, Isenberg D, Sumar N, et al. Changes in IgG glycoform levels are associated with remission of arthritis during pregnancy. J Autoimmun 1991; 4: 779–94.
View Full Article (HTML) Get PDF (95K)