Hemochromatosis and arthritis


  • H. Ralph Schumacher Jr. M.D.

    1. Fellow in Rheumatology, Southern California Chapter of the Arthritis and Rheumatism Foundation, Wadsworth
    2. Veterans Administration Hospital Los Angeles, California, Wadsworth
    3. Clinical Associate in Medicine, Department of Medicine, School of Medicine, University of California at Los Angeles
    Current affiliation:
    1. 103 Indiana Circle, Travis A.F.B., Calif
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Two patients with hemochromatosis and what appears to be a distinctive arthritis are presented. Both showed prominent involvement of the hands, minimal evidence of inflammation, significant x-ray changes and synovial hemosiderin deposition. Five other cases of a similar arthritis were found in a review of 23 cases of idiopathic hemochromatosis. The arthritis is postulated to be the result of iron excess damaging articular tissue in a yet undefined manner.


Es presentate le casos de duo patients con hemochromatosis e lo que esseva apparentemente un arthritis distinctive. Ambes monstrava prominente implication del manos, evidentia minime de inflammation, significative alterations radiologic, e deposition synovial de hemosiderina. In un revista de 23 casos de hemochromatosis idiopathic 5 altere casos de un simile arthritis esseva trovate. Es postulate que le arthritis es le resultato de excesso de ferro, lo que deteriora le tissu articular de un maniera nondum definite.