Hypophosphatasia associated with calcium pyrophosphate dihydrate deposits in cartilage

Authors

  • John D O'Duffy MD

    Corresponding author
    1. Section of Internal Medicine, Mayo Clinic, 200 First St SW, Rochester, Minn 55901.
    2. Department of Rheumatic Disease, The Cleveland Clinic Foundation, Cleveland, Ohio.
    • Department of Rheumatic Disease, The Cleveland Clinic Foundation, Cleveland, Ohio
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Abstract

A 51-year-old woman with hypophosphatasia had diffuse bone pain and widespread calcification in articular cartilage. Attacks of monarthritis had occurred for 27 years. Analysis of cartilage from the pubic symphysis revealed calcium pyrophosphate crystals.

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