Patterns of finger capillary abnormalities in connective tissue disease by “wide-field” microscopy

Authors

  • Hildegard Rand Maricq,

    Corresponding author
    1. Veterans Administration Hospital, Lyons, New Jersey, Essex County Hospital Center, Cedar Grove, New Jersey, and Columbia University College of Physicians and Surgeons, New York, New York.
    • Veterans Administration Hospital, Lyons, NJ 07939
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  • E. Carwile LeRoy

    1. Veterans Administration Hospital, Lyons, New Jersey, Essex County Hospital Center, Cedar Grove, New Jersey, and Columbia University College of Physicians and Surgeons, New York, New York.
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Abstract

The fingers of 75 patients with connective tissue disorders were examined by “wide-field” capillary microscopy. Four diagnostic groups were included in this study: rheumatoid arthritis—28, scleroderma—22, dermatomyositis—8, and systemic lupus erythematosus—17.On the basis of different patterns of elementary microvascular abnormalities and their distribution, 3 distinct groups were recognized among these patients: 1) increased visibility of nailfold subpapillary plexus in rheumatoid arthritis, 2) massive capillary dilatation in scleroderma-dermatomyositis, and 3) focal loss of capillaries and prominence of subpapillary vessels with “punched-out” lesions in systemic lupus erythematosus.

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