The 1982 revised criteria for the classification of systemic lupus erythematosus

Authors

  • Eng M. Tan MD,

    Corresponding author
    1. Chairman of Subcommittee for Systemic Lupus Erythematosus Criteria, Scripps Clinic and Research Foundation, La Jolla
    2. Subcommittee for Systemic Lupus Erythematosus Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee.
    • American Rheumatism Association, 1314 Spring Street, Atlanta, GA 30309
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  • Alan S. Cohen MD,

    1. Boston City Hospital, Boston
    2. Subcommittee for Systemic Lupus Erythematosus Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee.
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  • James F. Fries MD,

    1. Stanford University School of Medicine, Stanford
    2. Subcommittee for Systemic Lupus Erythematosus Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee.
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  • Alfonse T. Masi MD,

    1. University of Illinois College of Medicine, Peoria
    2. Subcommittee for Systemic Lupus Erythematosus Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee.
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  • Dennis J. Mcshane MD,

    1. Stanford University, Palo Alto
    2. Subcommittee for Systemic Lupus Erythematosus Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee.
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  • Naomi F. Rothfield MD,

    1. University of Connecticut School of Medicine, Farmington
    2. Subcommittee for Systemic Lupus Erythematosus Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee.
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  • Jane Green Schaller MD,

    1. University of Washington, Seattle
    2. Subcommittee for Systemic Lupus Erythematosus Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee.
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  • Norman Talal MD,

    1. VA Medical Center, San Francisco
    2. Subcommittee for Systemic Lupus Erythematosus Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee.
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  • Robert J. Winchester MD

    1. Hospital for Joint Diseases, New York.
    2. Subcommittee for Systemic Lupus Erythematosus Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee.
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Abstract

The 1971 preliminary criteria for the classification of systemic lupus erythematosus (SLE) were revised and updated to incorporate new immunologic knowledge and improve disease classification. The 1982 revised criteria include fluorescence antinuclear antibody and antibody to native DNA and Sm antigen. Some criteria involving the same organ systems were aggregated into single criteria. Raynaud's phenomenon and alopecia were not included in the 1982 revised criteria because of low sensitivity and specificity. The new criteria were 96% sensitive and 96% specific when tested with SLE and control patient data gathered from 18 participating clinics. When compared with the 1971 criteria, the 1982 revised criteria showed gains in sensitivity and specificity.

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