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References

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    Battisto JR, Smith RN, Beckman K, Sternlicht M, Welles WL: Susceptibility to adjuvant arthritis in DA and F344 rats: a dominant trait controlled by an autosomal gene locus linked to the major histocompatibility complex. Arthritis Rheum 25: 11941200, 1982
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    Pearson CM, Wood FD: Studies of polyarthritis and other lesions induced in rats by injection of mycobacterial adjuvant. I. General clinical and pathologic characteristics and some modifying factors. Arthritis Rheum 2: 440459, 1959
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    Pearson CM: Experimental models in rheumatoid arthritis. Arthritis Rheum 7: 8086, 1964
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    Ginsburg I: Can chronic and self-perpetuating arthritis in the human be caused by arthrotropic undegraded microbial cell wall constituents? A working hypothesis. Rheumatol Rehabil 16: 141149, 1977
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    Chang Y-H, Pearson CM, Abe C: Adjuvant polyarthritis. IV. Induction by a synthetic adjuvant: immunologic, histopathologic, and other studies. Arthritis Rheum 23: 6271, 1980
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    Ben-Nun A, Wekerle H, Cohen IR: The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis. Eur J Immunol 11: 195199, 1981
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    Ben-Nun A, Cohen IR: Experimental autoimmune encephalomyelitis (EAE) mediated by T cell lines: process of selection of lines and characterization of the cells. J Immunol 129: 303308, 1982
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    Holoshitz J, Naparstek Y, Ben-Nun A, Marquardt P, Cohen IR: T lymphocyte lines induce autoimmune encephalomyelitis, delayed hypersensitivity and bystander encephalitis or arthritis. Eur J Immunol 14: 729732, 1984
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    Yarom Y, Naparstek Y, Lev-Ram V, Holoshitz J, Ben-Nun A, Cohen IR: Immunospecific inhibition of nerve conduction in isolated rat optic nerve exerted by a line of T lymphocytes reactive to basic protein of myelin. Nature 303: 246247, 1983
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    Naparstek Y, Cohen IR, Fuks Z, Vlodavsky I: Activated T lymphocytes produce a matrix degrading heparan sulphate endoglycosidase. Nature 310: 241244, 1984
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    Ben-Nun A, Wekerle H, Cohen IR: Vaccination against autoimmune encephalomyelitis with T lymphocyte line cells reactive against myelin basic protein. Nature 292: 6061, 1981
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    Cohen IR, Ben-Nun A, Holoshitz J, Maron R, Zerubavel RL: Vaccination against autoimmune disease using lines of autoimmune T lymphocyte. Immunology Today 4: 227230, 1983
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    Maron R, Zerubavel R, Friedman A, Cohen IR: T lymphocyte line specific for thyroglobulin produces or vaccinates against autoimmune thyroiditis in mice. J Immunol 131: 23162322, 1983
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    Maron R, Cohen IR: H-2K mutation controls immune response phenotype of autoimmune thyroiditis: critical expression of mutant gene product in both thymus and thyroid glands. J Exp Med 152: 11151120, 1980
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    Janossy G, Panayi G, Duke O, Bofill M, Poulter LW, Goldstein G: Rheumatoid arthritis: a disease of T lymphocyte-macrophage immunization. Lancet ii: 839843, 1981
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    Holoshitz J, Naparstek Y, Ben-Nun A, Cohen IR: Lines of T lymphocytes induce or vaccinate against autoimmune arthritis. Science 219: 5658, 1983
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    Holoshitz J, Matitiau A, Cohen IR: Arthritis induced in rats by cloned T lymphocytes responsive to mycobacteria but not to collagen type II. J Clin Invest 73: 211215, 1984
  • 23
    Van Eden W, Holoshitz J, Nevo Z, Frenkel A, Klajman A, Cohen IR: Arthritis induced by a T lymphocyte clone that responds to Mycobacterium tuberculosis and to cartilage proteoglycans. Proc Natl Acad Sci USA (in press)
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    Holoshitz J, van Eden W, Reshef T, Cohen IR: Prevention and treatment of autoimmune arthritis by a T lymphocyte clone. Submitted for publication
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    Damle NK, Mohagheghpour N, Engleman EG: Soluble antigen-primed inducer T cells activate antigen-specific suppressor T cells in the absence of antigen-pulsed accessory cells: phenotypic definition of suppressor-inducer and suppressor-effector cells. J Immunol 132: 644650, 1984
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    Holoshitz J, Frenkel A, Ben-Nun A, Cohen IR: Autoimmune encephalomyelitis (EAE) mediated or prevented by T lymphocyte lines directed against diverse antigenic determinants of myelin basic protein: vaccination is determinant specific. J Immunol 131: 28102813, 1983
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    Holoshitz J, Matitiau A, Cohen IR: Role of the thymus in induction and transfer of vaccination against adjuvant arthritis with a T lymphocyte line in rats. J Clin Invest (in press)
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    Burnet FM: The Clonal Selection Theory of Acquired Immunity. Nashville, Vanderbilt University Press, 1959
  • 29
    Cohen IR: Autoimmunity: physiologic and pernicious. Adv Intern Med 29: 147165, 1984