• 1
    Budman DR, Merchant EB, Steinberg AD, Doft B, Gershwin ME, Lizzio E, Reeves JP: Increased spontaneous activity of antibody-forming cells in the peripheral blood of patients with active SLE. Arthritis Rheum 20: 829833, 1977
  • 2
    Bresnihan B, Jasin HE: Suppressor function of peripheral blood mononuclear cells in normal individuals and in patients with systemic lupus erythematosus. J Clin Invest 59: 106116, 1977
  • 3
    Steinberg AD, Smith HR, Laskin CA, Steinberg BJ, Smolen JS: Studies of immune abnormalities in systemic lupus erythematosus, Advances in Systemic Lupus Erythematosus. Edited by JPHayslett, JAHardin. New York, Grune & Stratton, 1983, pp 514
  • 4
    Tan EM: Autoantibodies to nuclear antigens (ANA): their immunobiology and medicine. Adv Immunol 33: 167240, 1982
  • 5
    Fauci AS, Steinberg AD, Haynes BF, Whalen G: Immunoregulatory aberrations in systemic lupus erythematosus. J Immunol 121: 14731479, 1978
  • 6
    Tan EM, Schur PH, Carr RI: Deoxyribonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythematosus. J Clin Invest 45: 17321740, 1966
  • 7
    Hardin JA, Thomas JO: Antibodies to histones in systemic lupus erythematosus: localization of prominent autoantigens on histones H1 and H2B. Proc Natl Acad Sci USA 80: 74107414, 1983
  • 8
    Hardin JA, Rahn DR, Shen C, Lerner MR, Wolin SL, Rosa MD, Steitz, JA: Antibodies from patients with connective tissue disease bind specific subsets of cellular RNA-protein particles. J Clin Invest 70: 141147, 1982
  • 9
    Mimori T, Akizuki M, Yamagata H, Inada S, Yoshida S, Homma M: Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies in sera from patients with polymyositis-scleroderma overlap. J Clin Invest 68: 611620, 1981
  • 10
    Yamada A, Shaw M, Winfield JB: Surface antigen specificity of cold-reactive IgM antilymphocyte antibodies in systemic lupus erythematosus. Arthritis Rheum 28: 4451, 1985
  • 11
    Pettersson I, Hinterberger M, Mimori T, Gottlieb E, Steitz JA: The structure of mammalian small nuclear ribonucleoproteins: identification of multiple protein components reactive with anti-(Ul)RNP and anti-Sm antibodies. J Biol Chem 259: 59075914, 1984
  • 12
    Wasicek CA, Reichlin M: Clinical and serological differences between systemic lupus erythematosus patients with antibodies to Ro versus patients with antibodies to Ro and La. J Clin Invest 70: 835843, 1982
  • 13
    Fritzler MJ, Rashid A, Tan EM: Antibodies from patients with mixed connective tissue disease react with heterogeneous nuclear ribonucleoprotein or ribonucleic acid (hnRNP/RNA) of the nuclear matrix. J Immunol 132: 12161222, 1984
  • 14
    Hardin JA, Gelpi C, Downs J, Mimori T: Autoantibodies to hnRNP in patients with SLE (abstract). Clin Res 33: 507A, 1985
  • 15
    Thomas JO, Wilson CM, Hardin JA: The major core histone antigenic determinants in systemic lupus erythematosus are in the trypsin-sensitive regions. FEBS Lett 169: 9096, 1984
  • 16
    Wolin S, Steitz JA: The Ro small cytoplasmic ribonucleoproteins: identification of the antigenic protein and its binding site on the Ro RNAs. Proc Natl Acad Sci USA 81: 19962000, 1984
  • 17
    Diamond B, Scharff MD: Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity. Proc Natl Acad Sci USA 81: 58415844, 1984
  • 18
    Lerner EA, Lerner MR, Janeway CA, Steitz JA: Monoclonal antibodies to nucleic acid-containing constituents: probes for molecular biology and autoimmune diseases. Proc Natl Acad Sci USA 78: 27372742, 1981
  • 19
    Pisetsky DS, Semper KF, Eisenberg RA: Idiotypic analysis of a monoclonal anti-Sm antibody. II. Strain distribution of a common idiotypic determinant and its relationship to anti-Sm expression. J Immunol 133: 20852089, 1984
  • 20
    Shoenfeld Y, Schwartz RS: Immunologic and genetic factors in autoimmune diseases. N Engl J Med 311: 10191029, 1984
  • 21
    Lefeber WP, Norris DA, Ryan SR, Huff JC, Lee LA, Kubo M, Boyce ST, Kotzin BL, Weston WL: Ultraviolet light induces binding of antibodies to select nuclear antigens on cultured human keratinocytes. J Clin Invest 74: 15451551, 1984
  • 22
    Craft JE, Bernstein RM, Hardin JA: Autoimmunity to histones in drug-induced lupus provides a model for anti-histone responses in spontaneous lupus (abstract). Clin Res 33: 505A, 1985
  • 23
    Schwartz RS, Stollar BD: Origins of anti-DNA autoantibodies. J Clin Invest 75: 321327, 1985
  • 24
    Richmond TJ, Finch JT, Rushton B, Rhodes D, Klug A: Structure of the nucleosome core particle at 7å resolution. Nature 311: 532537, 1984
  • 25
    Lerner MR, Steitz JA: Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus. Proc Natl Acad Sci USA 76: 54055499, 1979
  • 26
    Lerner MR, Boyle JA, Mount SM, Wolin SL, Steitz JA: Are snRNPs involved in splicing? Nature 283: 220224, 1980
  • 27
    Mount SM, Steitz JA: RNA splicing and the involvement of small ribonucleoproteins, Modern Cell Biology. Edited by BHSatir. New York, Alan Liss, 1984, pp 249297
  • 28
    Liautard JP, Sri-Widada J, Brumer C, Jeanteur P: Structured organization of ribonucleoproteins containing small nuclear RNAs from HeLa cells. J Mol Biol 162: 623643, 1982
  • 29
    Habets W, Hoet M, Bringmann P, Lührmann R, van Venrooji W: Autoantibodies to ribonucleoprotein particles containing U2 small nuclear RNA. EMBO J 4: 15451550, 1985
  • 30
    Stefano JE: Purified lupus antigen La recognizes an oligouridylate stretch common to the 3′ termini of RNA polymerase III transcripts. Cell 36: 145154, 1984