Tuberculous rheumatism (poncet's disease) in a child

Authors

  • T. R. Southwood BM, BS, FRACP,

    Pediatric Rheumatology Fellow
    1. Divisions of Rheumatology, Immunology, and General Pediatrics, Departments of Pediatrics and Pathology, University of British Columbia, Vancouver, British Columbia, Canada.
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  • E. J. Hancock PhD,

    Research Associate
    1. Divisions of Rheumatology, Immunology, and General Pediatrics, Departments of Pediatrics and Pathology, University of British Columbia, Vancouver, British Columbia, Canada.
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  • R. E. Petty MD, Phd, FAAP, FRCPC,

    Professor and Head
    1. Divisions of Rheumatology, Immunology, and General Pediatrics, Departments of Pediatrics and Pathology, University of British Columbia, Vancouver, British Columbia, Canada.
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  • P. N. Malleson MB, BS, MRCP(UK), FRCPC,

    Assistant Professor, Corresponding author
    1. Divisions of Rheumatology, Immunology, and General Pediatrics, Departments of Pediatrics and Pathology, University of British Columbia, Vancouver, British Columbia, Canada.
    • Division of Pediatric Rheumatology, Department of Pediatrics, The Research Center, 950 West 28th Avenue, Vancouver, British Columbia V5Z 4H4, Canada
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  • P. N. Thiessen MD, FRCPC

    Clinical Associate Professor
    1. Divisions of Rheumatology, Immunology, and General Pediatrics, Departments of Pediatrics and Pathology, University of British Columbia, Vancouver, British Columbia, Canada.
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Abstract

A 2-year-old boy who had increasing difficulty walking and had large, warm, sterile knee and ankle effusions was found to have active vertebral tuberculosis and a large prevertebral abscess. Lymphocyte proliferation assays demonstrated increased purified protein derivative-induced reactivity of synovial fluid lymphocytes compared with peripheral blood lymphocytes. The arthritis responded rapidly to antituberculous and antiinflammatory drugs. This patient's disease represented an example of tuberculous rheumatism (Poncet's disease).

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