Long-term disability and prolonged sick leaves as outcome measurements in ankylosing spondylitis: possible predictive factors

Authors

  • Francis Guillemin MD,

    Corresponding author
    1. Clinique de Rhumatologie, Unité Associée CNRS 1288, CHU de Nancy, and the Departement de Santé Publique, Faculté de Médecine, Nancy, France
    • Rhumatologie Service B. CHU de Nancy-Brabois, Vandoeuvre-les-Nancy 54500, France
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  • Serge Briançon MD,

    1. Clinique de Rhumatologie, Unité Associée CNRS 1288, CHU de Nancy, and the Departement de Santé Publique, Faculté de Médecine, Nancy, France
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  • Jacques Pourel MD,

    1. Clinique de Rhumatologie, Unité Associée CNRS 1288, CHU de Nancy, and the Departement de Santé Publique, Faculté de Médecine, Nancy, France
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  • Alain Gaucher MD

    1. Clinique de Rhumatologie, Unité Associée CNRS 1288, CHU de Nancy, and the Departement de Santé Publique, Faculté de Médecine, Nancy, France
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Abstract

Prognostic factors for the occurrence of longterm disability and prolonged sick leave were determined in 182 patients with ankylosing spondylitis. A significant relationship appeared between functional disability (determined by the Stanford Health Assessment Questionnaire) and sex, age at disease onset, and the number of peripheral joints involved. Using a life-table approach, the probability of prolonged sick leaves was associated with peripheral joint involvement and work that involved carrying heavy loads. Long-term disability was more frequent after work involving exposure to cold conditions (relative risk [RR] = 2.01) and prolonged standing postures (RR = 1.34), while sedentary work (RR = 0.35) and formal vocational rehabilitation programs (RR = 0.57) seemed to protect against long-term disability.

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