The American College of Rheumatology 1990 criteria for the classification of takayasu arteritis

Authors

  • William P. Arend MD,

    Corresponding author
    1. University of Colorado Health Science Center, Denver, CO
    • American College of Rheumatology, 17 Executive Park Drive NE, Atlanta, GA 30329
    Search for more papers by this author
  • Beat A. Michel MD,

    Corresponding author
    1. Rheumaklinik Universitätsspital, Zurich, Switzerland
    • American College of Rheumatology, 17 Executive Park Drive NE, Atlanta, GA 30329
    Search for more papers by this author
  • Daniel A. Bloch PhD,

    Corresponding author
    1. Stanford University, Stanford, CA
    • American College of Rheumatology, 17 Executive Park Drive NE, Atlanta, GA 30329
    Search for more papers by this author
  • Gene G. Hunder MD,

    Chair, Corresponding author
    1. Mayo Clinic, Rochester, MN Subcommittee on Classification of Vasculitis
    • American College of Rheumatology, 17 Executive Park Drive NE, Atlanta, GA 30329
    Search for more papers by this author
  • Leonard H. Calabrese DO,

    Corresponding author
    1. Cleveland Clinic Foundation, Cleveland, OH
    • American College of Rheumatology, 17 Executive Park Drive NE, Atlanta, GA 30329
    Search for more papers by this author
  • Steven M. Edworthy MD,

    Corresponding author
    1. University of Calgary, Calgary, Alberta, Canada
    • American College of Rheumatology, 17 Executive Park Drive NE, Atlanta, GA 30329
    Search for more papers by this author
  • Anthony S. Fauci MD,

    Corresponding author
    1. NIAID, NIH, Bethesda, MD
    • American College of Rheumatology, 17 Executive Park Drive NE, Atlanta, GA 30329
    Search for more papers by this author
  • Randi Y. Leavitt MD, PHD,

    Corresponding author
    1. NIAID, NIH, Bethesda, MD
    • American College of Rheumatology, 17 Executive Park Drive NE, Atlanta, GA 30329
    Search for more papers by this author
  • J. T. Lie MD,

    Corresponding author
    1. Mayo Clinic, Rochester, MN
    • American College of Rheumatology, 17 Executive Park Drive NE, Atlanta, GA 30329
    Search for more papers by this author
  • Robert W. Lightfoot Jr Md,

    Corresponding author
    1. University of Kentucky, Lexington, KY
    • American College of Rheumatology, 17 Executive Park Drive NE, Atlanta, GA 30329
    Search for more papers by this author
  • Alfonse T. Masi MD, Drph,

    Corresponding author
    1. University of Illinois College of Medicine, Peoria, IL
    • American College of Rheumatology, 17 Executive Park Drive NE, Atlanta, GA 30329
    Search for more papers by this author
  • Dennis J. McShane MD,

    Corresponding author
    1. Stanford University, Stanford, CA
    • American College of Rheumatology, 17 Executive Park Drive NE, Atlanta, GA 30329
    Search for more papers by this author
  • John A. Mills MD,

    Corresponding author
    1. Massachusetts General Hospital, Boston, MA
    • American College of Rheumatology, 17 Executive Park Drive NE, Atlanta, GA 30329
    Search for more papers by this author
  • Mary Betty Stevens MD,

    Corresponding author
    1. Johns Hopkins University, Baltimore, MD
    • American College of Rheumatology, 17 Executive Park Drive NE, Atlanta, GA 30329
    Search for more papers by this author
  • Stanley L. Wallace MD,

    Corresponding author
    1. SUNY Down-state Medical Center, Brooklyn, NY (Dr. Wallace is deceased)
    • American College of Rheumatology, 17 Executive Park Drive NE, Atlanta, GA 30329
    Search for more papers by this author
  • Nathan J. Zvaifler MD

    Corresponding author
    1. University of California, San Diego, San Diego, CA
    • American College of Rheumatology, 17 Executive Park Drive NE, Atlanta, GA 30329
    Search for more papers by this author

Abstract

Criteria for the classification of Takayasu arteritis were developed by comparing 63 patients who had this disease with 744 control patients with other forms of vasculitis. Six criteria were selected for the traditional format classification: onset at age ≤40 years, claudication of an extremity, decreased brachial artery pulse, >10 mm Hg difference in systolic blood pressure between arms, a bruit over the subclavian arteries or the aorta, and arteriographic evidence of narrowing or occlusion of the entire aorta, its primary branches, or large arteries in the proximal upper or lower extremities. The presence of 3 or more of these 6 criteria demonstrated a sensitivity of 90.5% and a specificity of 97.8%. A classification tree also was constructed with 5 of these 6 criteria, omitting claudication of an extremity. The classification tree demonstrated a sensitivity of 92.1% and a specificity of 97.0%.

Ancillary