Brief Report

Human immunodeficiency virus-associated psoriasis, psoriatic arthritis, and Reiter's syndrome: A disease continuum?

  1. John D. Reveille MD1,4,*,
  2. Marcus A. Conant MD2,4,
  3. Madeleine Duvic MD3,4

Article first published online: 9 DEC 2005

DOI: 10.1002/art.1780331016

Issue

Arthritis & Rheumatism

Arthritis & Rheumatism

Volume 33, Issue 10, pages 1574–1578, October 1990

Additional Information

How to Cite

Reveille, J. D., Conant, M. A. and Duvic, M. (1990), Human immunodeficiency virus-associated psoriasis, psoriatic arthritis, and Reiter's syndrome: A disease continuum?. Arthritis & Rheumatism, 33: 1574–1578. doi: 10.1002/art.1780331016

Author Information

  1. 1

    Department of Medicine, University of Texas Health Science Center at Houston

  2. 2

    University of California at San Francisco

  3. 3

    Departments of Medicine and Dermatology, University of Texas Health Science Center at Houston

  4. 4

    Division of Rheumatology and Clinical Immunogenetics, Department of Medicine, and the Department of Dermatology, The University of Texas Health Science Center at Houston, and the Department of Dermatology, The University of California at San Francisco

*University of Texas Health Science Center at Houston, Division of Rheumatology and Clinical Immunogenetics, PO Box 20708, Houston, TX 77225

Publication History

  1. Issue published online: 9 DEC 2005
  2. Article first published online: 9 DEC 2005
  3. Manuscript Accepted: 7 MAY 1990
  4. Manuscript Received: 4 DEC 1989

Funded by

  • Clinical Research Center. Grant Number: MO-1-RR-02558
  • Texas Health Science Center
  • Burroughs-Wellcome
  • NIH. Grant Numbers: AR-39325, ROI-AR39915-01
  • Arthritis Foundation Arthritis Investigator

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Abstract

The presence of peripheral arthritis and HLA-A, B, C, DR, and DQ antigens was evaluated prospectively in 18 Caucasian men with human immunodeficiency virus-associated psoriasis. An asymmetric polyarthritis occurred in 32% of the patients and correlated with the presence of HLA-B27. Extensive clinical overlap between psoriatic arthritis, psoriasis, and Reiter's syndrome was noted. No significant excess of the HLA antigens previously found to be associated with psoriasis was seen, which suggests that human immunodeficiency virus-associated psoriasis per se may instead constitute another form of spondylarthropathy that is more closely related to Reiter's syndrome.

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