SEARCH

SEARCH BY CITATION

Reference

  • 1
    Sandy JD, Sriratana A, Brown HLG, Lowther DA: Evidence for polymorphonuclear-derived proteinases in arthritic cartilage. Biochem J 193: 193202, 1981
  • 2
    MacNaul KL, Chartrain N, Lark M, Tocci MJ, Hutchinson NI: Discoordinate expression of stromelysin, collagenase, and TIMP-I in rheumatoid synovial fibroblasts. J Biol Chem 265: 1723817245, 1990
  • 3
    Murphy G, Hembry RM, Hughes CE, Fosang AJ, Hardingham TE: Role of regulation of metalloproteinases in connective tissue turnover. Biochem Soc Trans 18: 812815, 1990
  • 4
    Dean DD, Martel-Pelletier J, Pelletier J-P, Howell DS, Woessner JFJ: Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage. J Clin Invest 84: 678685, 1989
  • 5
    Gravallese EM, Darling JM, Laold AL, Katz JN, Glimcher LH: In situ hybridization studies of stromelysin and collagenase messenger RNA expression in rheumatoid synovium. Arthritis Rheum 34: 10761084, 1991
  • 6
    McCachren SS: Expression of metalloproteinases and metalloproteinase inhibitor in human arthritic synovium. Arthritis Rheum 34: 10851093, 1991
  • 7
    Walakovits LA, Moore VL, Bhardwaj N, Gallick GS, Lark MW: Detection of stromelysin and collagenase in synovial fluid from patients with rheumatoid arthritis and posttraumatic knee injury. Arthritis Rheum 35: 3542, 1992
  • 8
    Lohmander LS, Hoerrner LA, Lark MW: Metalloproteinases, tissue inhibitor, and proteoglycan fragments in knee synovial fluid in human osteoarthritis. Arthritis Rheum 36: 181189, 1993
  • 9
    Suzuki K, Shimizu K, Hamamoto T, Nakagawa Y, Hamakubo T, Yamamuro T: Biochemical demonstration of calpains and calpastatin in osteoarthritic synovial fluid. Arthritis Rheum 33: 728732, 1990
  • 10
    Suzuki K, Shimizu K, Hamamoto T, Nakagawa Y, Murachi T, Yamamoro T: Characterization of proteoglycan degradation by calpain. Biochem J 285: 857862, 1992
  • 11
    Buttle DJ, Saklatvala J: Lysosomal cysteine endopeptidases mediate interleukin-1 stimulated cartilage proteoglycan degradation. Biochem J 287: 657661, 1992
  • 12
    Campbell IK, Piccoli DS, Butler DM, Singleton DK, Hamilton JA: Recombinant human interleukin-1 stimulates human articular cartilage to undergo resorption and human chondrocytes to produce both tissue and urokinase-type plasminogen activator. Biochem Biophys Acta 967: 183194, 1988
  • 13
    Doege K, Sasaki M, Kimura T, Yamada Y: Complete coding sequence and deduced primary structure of the human cartilage large aggregating proteoglycan, aggrecan. J Biol Chem 266: 894902, 1991
  • 14
    Sandy JD, Flannery CR, Neame PJ, Lohmander LS: The structure of aggrecan fragments in human synovial fluid: evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain. J Clin Invest 89: 15121516, 1992
  • 15
    Flannery CR, Lark MW, Sandy JD: Identification of a stromelysin cleavage site within the interglobular domain of human aggrecan: evidence for proteolysis at this site in vivo in human articular cartilage. J Biol Chem 267: 10081014, 1991
  • 16
    Fosang AJ, Neame PJ, Last K, Hardingham TE, Murphy G, Hamilton JA: The interglobular domain of cartilage aggrecan is cleaved by PUMP, gelatinases and cathepsin B. J Biol Chem 267: 194701947 4, 1992
  • 17
    Flannery CR, Sandy JD: Aggrecan catabolism in cartilage: studies on the nature of a novel proteinase (aggrecanase) which cleaves the Glu-373-Ala 374 bond of the interglobular domain (abstract). Orthop Trans (in press)
  • 18
    Mok MT, Ilic MZ, Handley CJ, Robinson HC: Cleavage of proteoglycan aggregate by leukocyte elastase. Arch Biochem Biophys 292: 442447, 1992
  • 19
    Sandy JD, Neame PJ, Boynton RE, Flannery CR: Catabolism of aggrecan in cartilage explants: identification of a major cleavage site within the interglobular domain. J Biol Chem 266: 86838685, 1991
  • 20
    Ilic MZ, Handley CJ, Robinson HC, Mok MT: Mechanism of catabolism of aggrecan by articular cartilage. Arch Biochem Biophys 294: 115122, 1992
  • 21
    Loulakis P, Shrikhande A, Davis G, Maniglia CA: N-terminal sequence of proteoglycan fragments isolated from medium of interleukin-1 treated articular cartilage cultures. Biochem J 284: 589593, 1992
  • 22
    Plaas AHK, Sandy JD: A cartilage explant system for studies on aggrecan structure biosynthesis and catabolism in discrete zones of the mammalian growth plate. Matrix 13: 135147, 1993
  • 23
    Farndale RW, Buttle DJ, Barrett AJ: Improved quantitation and discrimination of sulphated glycosaminoglycan by use of dimethylmethylene blue. Biochim Biophys Acta 883: 173177, 1986
  • 24
    Caterson B, Christner JE, Couchman JR: Production and characterization of monoclonal antibodies directed against connective tissue proteoglycans. Fed Proc 44: 386393, 1985
  • 25
    Saxne T, Wollheim FA, Pettersson H, Heinegård D: Proteoglycan concentration in synovial fluid: predictor of future cartilage destruction in rheumatoid arthritis? Br Med J (Clin Res) 295: 14471448, 1987
  • 26
    Saxne T, Heinegård D, Wollheim FA: Cartilage proteoglycans in synovial fluid and serum in patients with inflammatory joint disease: relation to systemic treatment. Arthritis Rheum 30: 972979, 1987
  • 27
    Lohmander LS, Dahlberg L, Ryd L, Heinegård D: Increased levels of proteoglycan fragments in knee joint fluid after injury. Arthritis Rheum 32: 14341442, 1989
  • 28
    Saxne T, Heinegård D: Synovial fluid analysis of two groups of proteoglycan epitopes distinguishes early and late cartilage lesions. Arthritis Rheum 35: 385390, 1992
  • 29
    Dahlberg L, Ryd L, Heinegård D, Lohmander LS: Proteoglycan fragments in joint fluid: influence of arthrosis and inflammation. Acta Orthop Scand 63: 417423, 1992
  • 30
    Lohmander LS, Hoerrner LA, Dahlberg L, Roos H, Björnsson S, Lark MW: Metalloproteinases, tissue inhibitor and proteoglycan fragments in human knee joint fluid after injury. J Rheumatol (in press)
  • 31
    Lohmander LS: Markers of cartilage metabolism in arthrosis: a review. Acta Orthop Scand 62: 623632, 1991
  • 32
    Sandy JD: Extracellular metabolism of aggrecan, Articular Cartilage and Osteoarthritis. Edited by KKuettner, RSchleyerbach, JPeyron, VHascall. New York, Raven Press, 1992
  • 33
    Ahlbäck S: Osteoarthritis of the knee: a radiographic investigation. Acta Radiol Suppl (Stockh) 277: 772, 1968
  • 34
    Larsen A, Dale K, Eck M: Radiographic evaluation of rheumatoid arthritis and related conditions by standard reference films. Acta Radiol 18: 481491, 1977