Dynamic magnetic resonance imaging for the evaluation of synovitis in patients with rheumatoid arthritis
Article first published online: 9 DEC 2005
Copyright © 1994 American College of Rheumatology
Arthritis & Rheumatism
Volume 37, Issue 8, pages 1151–1157, December 1994
How to Cite
Tamai, K., Yamato, M., Yamaguchi, T. and Ohno, W. (1994), Dynamic magnetic resonance imaging for the evaluation of synovitis in patients with rheumatoid arthritis. Arthritis & Rheumatism, 37: 1151–1157. doi: 10.1002/art.1780370807
- Issue published online: 9 DEC 2005
- Article first published online: 9 DEC 2005
- Manuscript Accepted: 10 MAR 1994
- Manuscript Received: 5 MAY 1993
Objective. To investigate whether the findings of magnetic resonance imaging (MRI) reflect rheumatoid synovitis.
Methods. Dynamic imaging enhanced with gadolinium—diethylenetriamine pentaacetic acid was performed on 10 affected knees of 9 patients with rheumatoid arthritis. Changes in signal intensity were correlated with pathologic findings in synovial biopsy specimens obtained during total knee arthroplasty.
Results. Enhancement was greater in regions with a higher degree of fibrin exudation, cellular infiltration, villous hypertrophy, vascular proliferation, and granulation formation.
Conclusion. Dynamic MRI can be used for assessing local disease activity in rheumatoid synovium.