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References

  • 1
    Steinberg AD, Klinman DM: Pathogenesis of systemic lupus erythematosus. Rheum Dis Clin North Am 14: 2541, 1988
  • 2
    Becher TM, Lizzio EF, Mercant LP, Reeves JP, Steinberg AD: Increased multiclonal antibody-forming cell activation in the peripheral blood of patients with SLE. Int Arch Allerg Appl Immunol 66: 293298, 1981
  • 3
    Blaese RM, Grayson J, Steinberg AD: Elevated immunoglobulin secreting cells in the blood of patients with active systemic lupus erythematosus: correlation of laboratory and clinical assessment of disease activity. Am J Med 69: 345350, 1980
  • 4
    Tan PLJ, Pang GTM, Wilson JD, Cullinane G: Immunoglobulin secreting cells in SLE: correlation with disease activity. J Rheumatol 7: 807813, 1980
  • 5
    Klinman DM, Steinberg AD: Proliferation of anti-DNA producing NZB B cells in a non-autoimmune environment. J Immunol 137: 6975, 1986
  • 6
    Klinman DM, Steinberg AD: Similar in vivo expansion of B cells from normal DBA/2 and autoimmune NZB mice in xid recipients. J Immunol 139: 22842289, 1987
  • 7
    Steinberg AD, Gourley MF, Klinman DM, Tsokos GC, Scott DE, Krieg AM: Systemic lupus erythematosus. Ann Intern Med 115: 548559, 1991
  • 8
    Romagnami S: Induction of Th1 and T2 responses: a key role for the “natural” immune response? Immunol Today 13: 379381, 1992
  • 9
    Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL: Two types of murine helper T cell clones. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 136: 23482357, 1986
  • 10
    Romagnani S: Human Th1 and Th2 subsets: doubt no more. Immunol Today 12: 256257, 1991
  • 11
    Goldman M: Review: cytokines in the pathogenesis of systemic lupus erythematosus. Autoimmunity 8: 173179, 1990
  • 12
    Romagnani S: Lymphokine production by human T cells in disease states. Annu Rev Immunol 12: 227257, 1994
  • 13
    Linker-Israeli M, Deans R, Wallace D, Prehn J, Ozeri-Chen T, Klinenberg J: Elevated levels of endogenous IL-6 in systemic lupus erythematosus. J Immunol 147: 117123, 1991
  • 14
    Spronk P, Ter Borg E, Limburg P, Kallenberg C: Plasma concentration of IL-6 in systemic lupus erythematosus: an indicator of disease activity? Clin Exp Immunol 90: 106110, 1992
  • 15
    Al-Janadi M, Al-Balla S, Al-Dalaan A, Raziuddin S: Cytokine profile in systemic lupus erythematosus, rheumatoid arthritis, and other rheumatic diseases. J Clin Immunol 13: 5867, 1993
  • 16
    Ogawa N, Itoh M, Goto Y: Abnormal production of B cell growth factor in patients with systemic lupus erythematosus. Clin Exp Immunol 89: 2631, 1992
  • 17
    Hagiwara E, Klinman DM: Abnormalities in cytokine production and responsiveness in autoimmune disease. In, Cytokine Regulation and Humoral Immunity. Edited by CSnapper. Sussex, UK, John Wiley and Sons (in press)
  • 18
    Llorente L, Richaud-Patin Y, Wijdenes J, Alcocer-Varela J, Maillot M, Durand-Gasselin I, Fourrier B, Galanaud P, Emilie D: Spontaneous production of interleukin-10 by B lymphocytes and monocytes in systemic lupus erythematosus. Eur Cytokine Netw 4: 421430, 1993
  • 19
    Alarcon-Varela J, Alarcon-Segovia D: Decreased production of and response to IL-2 by cultured lymphocytes from patients with SLE. J Clin Invest 69: 13881393, 1982
  • 20
    Linker-Israeli M, Bakke AC, Kitridou RC, Gendler S, Gillis S, Horwitz DA: Defective production of IL-1 and IL-2 in patients with SLE. J Immunol 130: 26512658, 1983
  • 21
    Tsokos GC, Rook AH, Djeu JY, Balow JE: Natural killer cells and interferon response in patients with SLE. Clin Exp Immunol 50: 239246, 1982
  • 22
    Hagiwara E, Abbasi F, Mor G, Ishigatsubo Y, Klinman DM: Phenotype and frequency of cells secreting IL-2, IL-4, IL-6, IL-10, IFNγ, and TNFa in human peripheral blood. Cytokine (in press)
  • 23
    Klinman DM, Nutman TB: ELIspot assay to detect cytokinesecreting murine and human cells. In, Current Protocols in Immunology. Seventh edition. Edited by JEColigan, AMKruisbeek, DHMargulies, EMShevach, WStrober. Brooklyn, NY, Greene Publishing Associates, 1994
  • 24
    Cohen AS, Reynolds WE, Franklin EC, Kulka JP, Ropes MW, Wallace SL: Preliminary criteria for the classification of systemic lupus erythematosus. Bull Rheum Dis 21: 643647, 1971
  • 25
    Ishigatsubo Y, Sakamoto H, Hagiwara E, Aoki A, Shirai A, Tani K, Okubo T, Klinman DM: Quantitation of autoantibody-secreting B cells in systemic lupus erythematosus. Autoimmunity 5: 7180, 1990
  • 26
    Boyum A: Separation of leukocytes from blood and bone marrow. Scand J Clin Lab Invest 21: 7790, 1968
  • 27
    Semple J, Allen D, Chang W, Castaldi P, Freedman J: Rapid separation of CD4+ and CD19+ lymphocyte populations from human peripheral blood by a magnetic activated cell sorter (MACS). Cytometry 14: 955960, 1993
  • 28
    Kitani A, Hara M, Hirose T, Harigai M, Suzuki K, Kawakami M, Kawaguchi Y, Hidaka T, Kawagoe M, Nakamura H: Autostimulatory effects of IL-6 on excessive B cell differentiation in patients with systemic lupus erythematosus: analysis of IL-6 production and IL-6R expression. Clin Exp Immunol 88: 7583, 1992
  • 29
    Nagafuchi H, Suzuki N, Mizushima Y, Sakane T: Constitutive expression of IL-6 receptors and their role in the excessive B cell function in patients with systemic lupus erythematosus. J Immunol 151: 65256534, 1993
  • 30
    Kitani A, Hara M, Hirose T, Norioka K, Harigai M, Hirose W, Suzuki K, Kawakami M, Kawagoe M, Nakamura H: Heterogeneity of B cell responsiveness to interleukin 4, interleukin 6 and low molecular weight B cell growth factor in discrete stages of B cell activation in patients with systemic lupus erythematosus. Clin Exp Immunol 77: 3136, 1989
  • 31
    Linker-Israeli M: Cytokine abnormalities in human lupus. Clin Immunol Immunopathol 63: 1012, 1992
  • 32
    Shirai A, Conover J, Klinman DM: Increased activation and altered ratio of IFNγ.IL-4 secreting cells in MRL/lpr mice. Cytokine (in press)
  • 33
    Steinberg A, Krieg A, Gourley M, Klinman D: Theoretical and experimental approaches to generalized autoimmunity. Immunol Rev 118: 129163, 1990
  • 34
    Mor G, Klinman DM, Shapiro S, Hagiwara E, Sedegah M, Norman JA, Hoffman SL, Steinberg AD: Complexity of the cytokine and antibody response elicited by immunizing mice with PyCSP plasmid DNA. J Immunol (in press)
  • 35
    Klinman DM, Haynes BF, Conover J: Activation of IL-4 and IL-6 secreting cells by HIV-specific peptides. AIDS Res Hum Retroviruses 11: 97105, 1995
  • 36
    Shirai A, Holmes K, Klinman DM: Detection and quantitation of cells secreting IL-6 under physiological conditions in BALB/c mice. J Immunol 150: 793799, 1993