Presented in part at the 67th Annual Scientific Meeting of the American College of Rheumatology, Orlando, FL, October 2003.
Research Article
You have full text access to this OnlineOpen article
The risk of congestive heart failure in rheumatoid arthritis: A population-based study over 46 years†
Article first published online: 3 FEB 2005
DOI: 10.1002/art.20855
Copyright © 2005 by the American College of Rheumatology
Additional Information
How to Cite
Nicola, P. J., Maradit-Kremers, H., Roger, V. L., Jacobsen, S. J., Crowson, C. S., Ballman, K. V. and Gabriel, S. E. (2005), The risk of congestive heart failure in rheumatoid arthritis: A population-based study over 46 years. Arthritis & Rheumatism, 52: 412–420. doi: 10.1002/art.20855
- †
Publication History
- Issue published online: 3 FEB 2005
- Article first published online: 3 FEB 2005
- Manuscript Accepted: 10 NOV 2004
- Manuscript Received: 24 JUN 2004
Funded by
- NIH (National Institute of Arthritis and Musculoskeletal and Skin Diseases). Grant Number: R01-R-46849
- NIH/USPHS. Grant Number: AR-30582
- Luso-American Foundation
REFERENCES
- 1, , , , , , et al. Survival in rheumatoid arthritis: a population-based analysis of trends over 40 years. Arthritis Rheum 2003; 48: 54–8.Direct Link:
- 2. Recent improvements in survival in patients with rheumatoid arthritis: better outcomes or different study designs [concise communication]? Arthritis Rheum 2001; 44: 1467–9.Direct Link:
- 3, , , , . Cardiovascular death in rheumatoid arthritis: a population-based study. Arthritis Rheum. In press.
- 4, , . All-cause mortality and vascular events among patients with RA, OA, or no arthritis in the UK General Practice Research Database. J Rheumatol 2003; 30: 1196–202.
- 5, , , . Shortening of life span and causes of excess mortality in a population-based series of subjects with rheumatoid arthritis. Clin Exp Rheumatol 1995; 13: 149–53.
- 6, , , , , . Mortality in early inflammatory polyarthritis: cardiovascular mortality is increased in seropositive patients. Arthritis Rheum 2002; 46: 2010–9.Direct Link:
- 7, , . Increase in cardiovascular and cerebrovascular disease prevalence in rheumatoid arthritis. J Rheumatol 2003; 30: 36–40.
- 8, , , , , , et al. Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis. Circulation 2003; 107: 1303–7.
- 9. Prevalence of self-reported heart failure among US adults: results from the 1999 National Health Interview Survey. Am Heart J 2003; 146: 121–8.
- 10, , , , , , et al. The incidence and prevalence of congestive heart failure in Rochester, Minnesota. Mayo Clin Proc 1993; 68: 1143–50.
- 11
- 12, , , , , , et al. Survival of patients with a new diagnosis of heart failure: a population based study. Heart 2000; 83: 505–10.
- 13, . Pathophysiological role of cytokines in congestive heart failure. Annu Rev Med 2001; 52: 15–27.
- 14, , . Cytokines as new treatment targets in chronic heart failure. Curr Control Trials Cardiovasc Med 2001; 2: 271–7.
- 15, , , , , , et al. Diastolic function abnormalities in rheumatoid arthritis: evaluation by echo Doppler transmitral flow and pulmonary venous flow: relation with duration of disease. Ann Rheum Dis 2000; 59: 227–9.
- 16, , , , , , et al. Impaired diastolic function in active rheumatoid arthritis: relationship with disease duration. Clin Exp Rheumatol 1999; 17: 407–12.
- 17, , , , . Ventricular function abnormalities in active rheumatoid arthritis: a Doppler echocardiographic study. Rheumatol Int 2004; 24: 141–6.
- 18, , . Comorbidity in arthritis. J Rheumatol 1999; 26: 2475–9.
- 19, . Heart failure in rheumatoid arthritis: rates, predictors, and the effect of anti-tumor necrosis factor therapy. Am J Med 2004; 116: 305–11.
- 20, . The patient record in epidemiology. Sci Am 1981; 245: 54–63.
- 21. History of the Rochester Epidemiology Project. Mayo Clin Proc 1996; 71: 266–74.
- 22, , . The epidemiology of rheumatoid arthritis in Rochester, Minnesota, 1955–1985. Arthritis Rheum 1999; 42: 415–20.Direct Link:
- 23, , , , , , et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 315–24.Direct Link:
- 24, , , . The epidemiology of heart failure: the Framingham Study. J Am Coll Cardiol 1993; 22 Suppl A: 6A–13A.
- 25, , , , , , et al. Classification of heart failure in population based research: an assessment of six heart failure scores. Eur J Epidemiol 1997; 13: 491–502.
- 26Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA 2001; 285: 2486–97.
- 27
- 28The sixth report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure. Arch Intern Med 1997; 157: 2413–46.
- 29Expert Panel on the Identification, Evaluation, and Treatment of Overweight in Adults. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: executive summary. Am J Clin Nutr 1998; 68: 899–917.
- 30, , , . International diagnostic criteria for acute myocardial infarction and acute stroke. Am Heart J 1984: 150–8.
- 31, , . The Minnesota Code Manual of Electrocardiographic Findings: Standards and Procedures for Measurement and Classification. Littleton (MA): Wright-PSG; 1982.
- 32, , , , , , et al. Trends in the incidence and survival of patients with hospitalized myocardial infarction, Olmsted County, Minnesota, 1979 to 1994. Ann Intern Med 2002; 136: 341–8.
- 33. Some simple approximate tests or Poisson variates. Biometrika 1953; 40: 354–60.
- 34, , , . Estimation of failure probabilities in the presence of competing risks: new representations of old estimators. Stat Med 1999; 18: 695–706.Direct Link:
- 35, . Influence. In: TherneauTM, GrambschPM, editors. Modeling survival data: extending the Cox model. New York: Springer-Verlag; 2000. p. 153–68.
- 36, , , , , . Risk factors for congestive heart failure in US men and women: NHANES I epidemiologic follow-up study. Arch Intern Med 2001; 161: 996–1002.
- 37, , , , , , et al. Increased unrecognized coronary heart disease in rheumatoid arthritis: a population-based cohort study. Arthritis Rheum 2005; 52: 402–11.Direct Link:
- 38, , , , , , et al. Increased levels of C-reactive protein in serum from blood donors before the onset of rheumatoid arthritis. Arthritis Rheum 2004; 50: 2423–7.Direct Link:
- 39, , , , , , et al. Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis. Arthritis Rheum 2003; 48: 2741–9.Direct Link:
- 40, , , , , , et al. Specific autoantibodies precede the symptoms of rheumatoid arthritis: a study of serial measurements in blood donors. Arthritis Rheum 2004; 50: 380–6.Direct Link:
- 41, , , , , , et al. Inflammatory markers and onset of cardiovascular events: results from the Health ABC study. Circulation 2003; 108: 2317–22.
- 42, , , , , , et al. Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study. Circulation 2003; 107: 1486–91.
- 43, . Proinflammatory cytokines: predictors of a failing heart? Circulation 2003; 107: 1460–2.
- 44, , . Echocardiographic findings and 24-h electrocardiographic Holter monitoring in patients with nodular and non-nodular rheumatoid arthritis. Rheumatol Int 1999; 18: 163–9.
- 45, , . Cardiac involvement in rheumatoid disease. Clin Med 2001; 1: 18–21.
- 46, , , , . Occurrence of extraarticular disease manifestations is associated with excess mortality in a community based cohort of patients with rheumatoid arthritis. J Rheumatol 2002; 29: 62–7.
- 47, . Consumption of NSAIDs and the development of congestive heart failure in elderly patients: an underrecognized public health problem. Arch Intern Med 2000; 160: 777–84.
- 48
- 49, , , , . Diagnosis of chloroquine cardiomyopathy by endomyocardial biopsy. N Engl J Med 1987; 316: 191–3.
- 50, , . Chloroquine cardiomyopathy with conduction disorders. Heart 1999; 81: 221–3.
- 51, , . D-penicillamine induced polymyositis causing complete heart block. Clin Rheumatol 1994; 13: 80–2.
- 52, , , , . Methotrexate and mortality in patients with rheumatoid arthritis: a prospective study. Lancet 2002; 359: 1173–7.
- 53, , . Mortality in early “sawtooth” treated rheumatoid arthritis patients during the first 8–14 years. Scand J Rheumatol 1999; 28: 282–7.
- 54, , , . Extent of inflammation predicts cardiovascular disease and overall mortality in seropositive rheumatoid arthritis: a retrospective cohort study from disease onset. J Rheumatol 1999; 26: 2562–71.
- 55, , . Cardiovascular morbidity and mortality in patients with seropositive rheumatoid arthritis in Northern Sweden. J Rheumatol 1997; 24: 445–51.
- 56, , , , . Survival and drug discontinuation analyses in a large cohort of methotrexate treated rheumatoid arthritis patients. Ann Rheum Dis 1995; 54: 708–12.
- 57, , , , , , et al. Rheumatoid arthritis and mortality: a longitudinal study in Pima Indians. Arthritis Rheum 1993; 36: 1045–53.Direct Link:
- 58, , , . Cardiovascular mortality in patients with rheumatoid arthritis. Cardiology 1989; 76: 71–7.
- 59, , , , , , et al. Trends in heart failure incidence and survival in a community-based population. JAMA 2004; 292: 344–50.

1529-0131/asset/olbannerleft.gif?v=1&s=897b81612b4ad6cae003112184adc709261d5f61)
1529-0131/asset/olbannerright.gif?v=1&s=04654f5ea3cbb01656383e0c0d04b16fd0a9a896)
