SEARCH

SEARCH BY CITATION

REFERENCES

  • 1
    Firestein GS. Evolving concepts of rheumatoid arthritis. Nature 2003; 423: 35661.
  • 2
    Salmon M, Scheel-Toellner D, Huissoon AP, Pilling D, Shamsadeen N, Hyde H, et al. Inhibition of T cell apoptosis in the rheumatoid synovium. J Clin Invest 1997; 99: 43946.
  • 3
    Mountz JD, Hsu H-C, Matsuki Y, Zhang H-G. Apoptosis and rheumatoid arthritis: past, present and future directions. Curr Rheum Rep 2001; 3: 708.
  • 4
    Weyand CM, Goronzy JJ, Takemura S, Kutin PJ. Cell-cell interactions in synovitis: interactions between T cells and B cells in rheumatoid arthritis. Arthritis Res 2000; 2: 45763.
  • 5
    Ospelt C, Neidhart M, Gay RE, Gay S. Synovial activation in rheumatoid arthritis. Front Biosci 2004; 9: 232334.
  • 6
    Perlman H, Pagliari LJ, Liu H, Koch AE, Haines GK, Pope RM. Rheumatoid arthritis synovial macrophages express the Fas-associated death domain–like interleukin-1β–converting enzyme-inhibitory protein and are refractory to Fas-mediated apoptosis. Arthritis Rheum 2001; 44: 2130.
  • 7
    Kim G, Jun J-B, Elkon KB. Necessary role of phosphatidylinositol 3-kinase in transforming growth factor β–mediated activation of Akt in normal and rheumatoid arthritis synovial fibroblasts. Arthritis Rheum 2002; 46: 150411.
  • 8
    Kotzin BL. The role of B cells in the pathogenesis of rheumatoid arthritis. J Rheumatol 2005; 73: 148.
  • 9
    Schroder AE, Greiner A, Seyfert C, Berek C. Differentiation of B cells in the nonlymphoid tissue of the synovial membrane of patients with rheumatoid arthritis. Proc Natl Acad Sci U S A 1996; 93: 2215.
  • 10
    Dechanet J, Merville P, Durand I, Banchereau J, Miosec P. The ability of synoviocytes to support terminal differentiation of activated B cells may explain plasma cell accumulation in rheumatoid synovium. J Clin Invest 1995; 95: 45663.
  • 11
    Hayashida K, Shimaoka Y, Ochi T, Lipsky PE. Rheumatoid arthritis synovial stromal cells inhibit apoptosis and up-regulate Bcl-xL expression by B cells in a CD49/CD29-CD106-dependent mechanism. J Immunol 2000; 164: 11106.
  • 12
    Takemura S, Klimiuk PA, Braun A, Goronzy JJ, Weyand CM. T cell activation in rheumatoid synovium is B cell dependent. J Immunol 2001; 167: 47108.
  • 13
    Edwards JC, Szczepanski L, Szechinski J, Fillipowicz-Sosnowska A, Emery PE, Close DR, et al. Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis. N Engl J Med 2004; 350: 257281.
  • 14
    Martin F, Chan AC. Pathogenic roles of B cells in human autoimmunity: insights from the clinic. Immunity 2004; 20: 51727.
  • 15
    Wagner U, Kaltenhauser S, Pierer M, Wilke B, Arnold S, Hantzschel H. B lymphocytopenia in rheumatoid arthritis is associated with the DRB1 shared epitope and increased acute phase response. Arthritis Res 2002; 4: R1.
  • 16
    Symmons DP, Farr M, Salmon M, Bacon PA. Lymphopenia in rheumatoid arthritis. J R Soc Med 1989; 82: 4623.
  • 17
    Rosen H, Goetzl EJ. Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network. Nat Rev Immunol 2005; 5: 56070.
  • 18
    Cinamon G, Matloubian M, Lesneski MJ, Xu Y, Low C, Lu T, et al. Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone. Nat Immunol 2004; 5: 71320.
  • 19
    Tosato G. Generation of Epstein-Barr virus (EBV)-immortalized B cell lines. In: ColiganJE, KruisbeekAM, MarguliesDH, ShevachEM, StroberW, editors. Current protocols in immunology. New York: John Wiley & Sons; 1998. p. 7.22.17.22.3.
  • 20
    Huang P, Plunkett W. A quantitative assay for fragmented DNA in apoptotic cells. Anal Biochem 1992; 207: 1637.
  • 21
    Gorczyca W, Bigman K, Mittelman A, Ahmed T, Gong J, Melamed MR, et al. Induction of DNA strand breaks associated with apoptosis during treatment of leukemias. Leukemia 1993; 7: 65970.
  • 22
    Stennicke HR, Salvesen GS. Biochemical characteristics of caspases-3, -6, -7, and -8. J Biol Chem 1997; 272: 2571923.
  • 23
    Yatomi Y, Ruan F, Ohta J, Welch RJ, Hakomori S, Igarashi Y. Quantitative measurement of sphingosine-1-phosphate in biological samples by acylation with radioactive acetic anhydride. Anal Biochem 1995; 230: 31520.
  • 24
    Ancellin N, Colmont C, Su J, Li Q, Mittereder N, Chae SS, et al. Extracellular export of sphingosine kinase-1 enzyme: sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation. J Biol Chem 2002; 277: 666775.
  • 25
    Gregersen PK, Silver J, Winchester RJ. The shared epitope hypothesis: an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum 1987; 30: 120513.
  • 26
    Spiegel S, Cuvillier O, Furior E, Milstein S. Sphingosine-1-phosphate: member of a new class of lipid second messengers. In: HannunY, editor. Sphingolipid-mediated signal transduction. Georgetown (TX): R. G. Landes Company; 1997. p. 12135.
  • 27
    Siffert W, Rosskopf D, Moritz A, Wieland T, Kaldenberg-Stasch S, Kettler N, et al. Enhanced G protein activation in immortalized lymphoblasts from patients with essential hypertension. J Clin Invest 1995; 96: 75966.
  • 28
    Negre A, Salvayre R, Maret A, Vieu C, Bes JC, Borrone C, et al. Lymphoid cell lines as a model system for the study of Wolman's disease: enzymatic, metabolic and ultrastructural investigations. J Inherit Metab Dis 1986; 9: 193201.
  • 29
    Maret A, Salvayre R, Samadi M, Douste-Blazy L. Beta glucosidase isoenzymes in Epstein-Barr virus transformed lymphoid cell lines from normal subjects and patients with type 1 Gaucher disease. Enzyme 1987; 37: 20817.
  • 30
    Thrasher A, Segal A, Casimir C. Chronic granulomatous disease: toward gene therapy. Immunodeficiency 1993; 4: 32733.
  • 31
    Negrier C, Vinciguerra C, Attali O, Grenier C, Larcher ME, Dechavanne M. Illegitimate transcription: its use for studying genetic abnormalities in lymphoblastoid cells from patients with Glanzmann thrombasthenia. Br J Haematol 1998; 100: 339.
  • 32
    Lostanlen D, Lenoir G, Kaplan JC. NADH cytochrome b5 reductase activity in lymphoid cell lines: expression of the defect in Epstein-Barr virus transformed lymphoblastoid cell lines from patients with recessive congenital methemoglobinemia. J Clin Invest 1981; 68: 27985.
  • 33
    Rao NM, Joshi NN, Shinde SR, Advani SH, Ghosh SN. Premature separation of centromere and aneuploidy: an indicator of high risk in unaffected individuals from familial breast cancer families? Eur J Cancer Prev 1996; 5: 34350.
  • 34
    Silman AJ, MacGregor AJ, Thomson W, Holligan S, Carthy D, Farhan A, et al. Twin concordance rates for rheumatoid arthritis: results from a nationwide study. Br J Rheumatol 1993; 32: 9037.
  • 35
    Mizuno T, Zhong X, Rothstein TL. Fas-induced apoptosis in B cells. Apoptosis 2003; 8: 45160.
  • 36
    Sobel ES, Kakkanaiah VN, Schiffenbauer J, Reap EA, Cohen PL, Eisenberg RA. Novel immunoregulatory B cell pathways revealed by lpr-+ mixed chimeras. J Immunol 1998; 160: 1497503.
  • 37
    Nemazee D, Guiet C, Buerki K, Marshak-Rothstein A. B lymphocytes from the autoimmune-prone mouse strain MLR/lpr manifest an intrinsic defect in tetraparental MRL/lpr in equilibrium DBA/2 chimeras. J Immunol 1991; 147: 25369.
  • 38
    Di Cristofano A, Kotsi P, Peng YF, Cordon-Cardo C, Elkon KB, Pandolfi PP. Impaired Fas response and autoimmunity in Pten +/− mice. Science 1999; 285: 21225.
  • 39
    Ohata J, Zvaifler NJ, Nishio M, Boyle DL, Kalled SL, Carson DA, et al. Fibroblast-like synoviocytes of mesenchymal origin express functional B cell-activating factor of the TNF family in response to proinflammatory cytokines. J Immunol 2005; 174: 86470.
  • 40
    Mackay F, Woodcock SA, Lawton P, Ambrose C, Baetscher M, Schneider P, et al. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J Exp Med 1999; 190: 1697710.
  • 41
    Olivera A, Kohama T, Edsall L, Nava V, Cuvillier O, Poulton S, et al. Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival. J Cell Biol 1999; 147: 54558.
  • 42
    Igarashi N, Okada T, Hayashi S, Fujita T, Jahangeer S, Nakamura S. Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis. J Biol Chem 2003; 278: 468329.
  • 43
    Liu H, Toman RE, Goparaju SK, Maceyka M, Nava VE, Sankala H, et al. Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis. J Biol Chem 2003; 278: 403306.
  • 44
    Remmers EF, Longman RE, Du Y, O'Hare A, Cannon GW, Griffiths MM, et al. A genome scan localizes five non-MHC loci controlling collagen-induced arthritis in rats. Nat Genet 1996; 14: 825.
  • 45
    Tosato G, Steinberg AD, Yarchoan R, Heilman CA, Pike SE, De-Seau V, et al. Abnormally elevated frequency of Epstein-Barr virus-infected B cells in the blood of patients with rheumatoid arthritis. J Clin Invest 1984; 73: 178995.
  • 46
    Imamura T, Miyauchi-Senda N, Tanaka S, Shiota K. Identification of genetic and epigenetic similarities of SPHK1/Sphk1 in mammals. J Vet Med Sci 2004; 66: 138793.
  • 47
    Cuvillier O, Pirianov G, Kleuser B, Vanek PG, Coso OA, Gutkind S, et al. Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature 1996; 381: 8003.
  • 48
    Maceyaka M, Payne SG, Milstein S, Spiegel S. Sphingosine kinase, sphingosine-1-phosphate, and apoptosis. Biochim Biophys Acta 2002; 1585: 193201.
  • 49
    Rosen H, Sanna G, Alfonso C. Egress: a receptor-regulated step in lymphocyte trafficking. Immunol Rev 2003; 195: 1607.
  • 50
    Brinkmann V, Cyster JG, Hla T. FTY720: sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function. Am J Transplant 2004; 4: 101925.
  • 51
    Matsuura M, Imayoshi T, Okumoto T. Effect of FTY720, a novel immunosuppressant on adjuvant-induced arthritis in rats. Int J Immunol 2000; 22: 32331.