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Acupuncture in patients with osteoarthritis of the knee or hip: A randomized, controlled trial with an additional nonrandomized arm

  1. Claudia M. Witt1,*,
  2. Susanne Jena1,
  3. Benno Brinkhaus1,
  4. Bodo Liecker2,
  5. Karl Wegscheider3,
  6. Stefan N. Willich1

Article first published online: 30 OCT 2006

DOI: 10.1002/art.22154

Issue

Arthritis & Rheumatism

Arthritis & Rheumatism

Volume 54, Issue 11, pages 3485–3493, November 2006

Additional Information

How to Cite

Witt, C. M., Jena, S., Brinkhaus, B., Liecker, B., Wegscheider, K. and Willich, S. N. (2006), Acupuncture in patients with osteoarthritis of the knee or hip: A randomized, controlled trial with an additional nonrandomized arm. Arthritis & Rheumatism, 54: 3485–3493. doi: 10.1002/art.22154

Author Information

  1. 1

    Charité University Medical Center, Berlin, Germany

  2. 2

    Techniker Krankenkasse, Hamburg, Germany

  3. 3

    University of Hamburg, Hamburg, Germany

*Institute for Social Medicine, Epidemiology, and Health Economics, Charité University Medical Center, 10098 Berlin, Germany

Publication History

  1. Issue published online: 30 OCT 2006
  2. Article first published online: 30 OCT 2006
  3. Manuscript Accepted: 11 JUL 2006
  4. Manuscript Received: 3 APR 2006

Funded by

  • Techniker Krankenkasse
  • Betriebskrankenkasse (BKK) Aktiv
  • Bosch BKK
  • DaimlerChrysler BKK
  • Bertelsmann BKK
  • BKK BMW
  • Siemens-Betriebskrankenkasse
  • BKK Deutsche Bank
  • BKK Hoechst
  • HypoVereinsbank BKK
  • Ford BKK
  • Betriebskrankenkasse der Allianz Gesellschaften
  • Vereins- und Westbank BKK
  • Handelskrankenkasse
  • Innungskrankenkasse Hamburg

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REFERENCES

  • 1
    Badley EM, Webster GK, Rasooly I. The impact of musculoskeletal disorders in the population: are they just aches and pains? Findings from the 1990 Ontario Health Survey. J Rheumatol 1995; 22 : 733–9.
  • 2
    Creamer P, Hochberg MC. Osteoarthritis. Lancet 1997; 350: 503–8.
  • 3
    Tramer MR, Moore RA, Reynolds DJ, McQuay HJ. Quantitative estimation of rare adverse events which follow a biological progression: a new model applied to chronic NSAID use. Pain 2000; 85: 169–82.
  • 4
    American College of Rheumatology Subcommittee on Osteoarthritis Guidelines. Recommendations for the medical management of osteoarthritis of the hip and knee: 2000 update. Arthritis Rheum 2000; 43: 1905–15.
    Direct Link:
  • 5
    Eisenberg DM, Davis RB, Ettner SL, Appel S, Wilkey S, van Rompay M, et al. Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. JAMA 1998; 280: 1569–75.
  • 6
    Ezzo J, Hadhazy V, Birch S, Lao L, Kaplan G, Hochberg M, et al. Acupuncture for osteoarthritis of the knee: a systematic review. Arthritis Rheum 2001; 44: 819–25.
    Direct Link:
  • 7
    Berman BM, Lao L, Langenberg P, Lee WL, Gilpin AM, Hochberg MC. Effectiveness of acupuncture as adjunctive therapy in osteoarthritis of the knee: a randomized, controlled trial. Ann Intern Med 2004; 141: 901–10.
  • 8
    Witt C, Brinkhaus B, Jena S, Linde K, Streng A, Wagenpfeil S, et al. Acupuncture in patients with osteoarthritis of the knee: a randomised trial. Lancet 2005; 366: 136–43.
  • 9
    Announcement of a guideline change for the assessment of medical diagnostic and treatment methods. Section 135, Social Security Code V (BUB guideline).
  • 10
    European Epidemiology Federation. Good Epidemiological Practice (GEP): proper conduct in epidemiological research. 2004. URL: www.dundee.ac.uk/iea/GoodPract.htm.
  • 11
    Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol 1988; 15: 1833–40.
  • 12
    Stucki G, Meier D, Stucki S, Michel BA, Tyndall AG, Dick W, et al. Evaluation of a German version of WOMAC (Western Ontario and McMaster Universities) Arthrosis Index. Z Rheumatol 1996; 55: 40–9. In German.
  • 13
    Bullinger M, Kirchberger I. SF-36 quality of life questionnaire. Göttingen (Germany): Hogrefe; 1998.
  • 14
    Bellamy N, Kirwan J, Boers M, Brooks P, Strand V, Tugwell P, et al. Recommendations for a core set of outcome measures for future phase III clinical trials in knee, hip, and hand osteoarthritis: consensus development at OMERACT III. J Rheumatol 1997; 24: 799–802.
  • 15
    Salaffi F, Carotti M, Grassi W. Health-related quality of life in patients with hip or knee osteoarthritis: comparison of generic and disease-specific instruments. Clin Rheumatol 2005; 24: 29–37.
  • 16
    Svensson O, Malmenas M, Fajutrao L, Roos EM, Lohmander S. Greater reduction of knee than hip pain in osteoarthritis treated with naproxen, as evaluated by WOMAC and SF-36. Ann Rheum Dis 2006; 65: 781–4.
  • 17
    Creel AH, Losina E, Mandl LA, Marx RJ, Mahomed NN, Martin SD, et al. An assessment of willingness to participate in a randomized trial of arthroscopic knee surgery in patients with osteoarthritis. Contemp Clin Trials 2005; 26: 169–78.
  • 18
    Concato J, Shah N, Horwitz RI. Randomized, controlled trials, observational studies, and the hierarchy of research designs. N Engl J Med 2000; 342: 1887–92.
  • 19
    Tubach F, Ravaud P, Baron G, Falissard B, Logeart I, Bellamy N, et al. Evaluation of clinically relevant changes in patient-reported outcomes in knee and hip osteoarthritis: the minimal clinically important improvement. Ann Rheum Dis 2005; 64: 29–33.
  • 20
    Berman BM, Singh BB, Lao L, Langenberg P, Li H, Hadhazy V, et al. A randomized trial of acupuncture as an adjunctive therapy in osteoarthritis of the knee. Rheumatology (Oxford) 1999; 38: 346–54.
  • 21
    Christensen BV, Luhl IU, Vilbek H, Bulow HH, Dreijer NC, Rasmussen HF. Acupuncture treatment of severe knee osteoarthrosis: a long-term study. Acta Anaesthesiol Scand 1992; 36: 519–25.
    Direct Link:
  • 22
    Tillu A, Tillu S, Vowler S. Effect of acupuncture on knee function in advanced osteoarthritis of the knee: a prospective, non-randomised controlled study. Acupunct Med 2002; 20: 19–21.
  • 23
    White A, Hayhoe S, Hart A, Ernst E. Adverse events following acupuncture: prospective survey of 32,000 consultations with doctors and physiotherapists. BMJ 2001; 323: 485–6.
  • 24
    MacPherson H, Thomas K, Walters S, Fitter M. The York acupuncture safety study: prospective survey of 34 000 treatments by traditional acupuncturists. BMJ 2001; 323: 486–7.
  • 25
    Melchart D, Weidenhammer W, Streng A, Reitmayr S, Hoppe A, Ernst E, et al. Prospective investigation of adverse effects of acupuncture in 97 733 patients. Arch Intern Med 2004; 164: 104–5.
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