Correct citation regarding interleukin-6 levels in cerebrospinal fluid from patients with neuropsychiatric lupus: Comment on the article by Fragoso-Loyo et al


Correct Citation Regarding Interleukin-6 Levels in Cerebrospinal Fluid from Patients with Neuropsychiatric Lupus: Comment on the Article by Fragoso-Loyo et al

To the Editor:

I read with interest the report by Fragoso-Loyo et al (1) describing the quantification of interleukin-6 (IL-6) and chemokines in cerebrospinal fluid (CSF) as an accurate indicator of neuropsychiatric involvement in systemic lupus erythematosus (NPSLE) that could be useful in the followup and evaluation of treatment response in these patients. It is always a pleasure when our observations are confirmed and extended by other investigators. However, Fragoso-Loyo and colleagues cited the wrong paper as their reference 10: our article in Clinical Immunology and Immunopathology (2), in which no data on NPSLE were included. We reported the elevated levels of IL-6 in CSF from patients with NPSLE in Arthritis & Rheumatism in 1990 (3). Therefore, Fragoso-Loyo et al should refer to this report instead of our paper in Clinical Immunology and Immunopathology, and provide comments on the relevance of our findings to theirs.

Shunsei Hirohata MD*, * Kitasato University School of Medicine, Kanagawa, Japan.