Dr. Bar-Or is deceased.
The effects of vigorous exercise training on physical function in children with arthritis: A randomized, controlled, SINGLE-BLINDED trial†
Article first published online: 28 SEP 2007
Copyright © 2007 by the American College of Rheumatology
Arthritis Care & Research
Volume 57, Issue 7, pages 1202–1210, 15 October 2007
How to Cite
Singh-Grewal, D., Schneiderman-Walker, J., Wright, V., Bar-Or, O., Beyene, J., Selvadurai, H., Cameron, B., Laxer, R. M., Schneider, R., Silverman, E. D., Spiegel, L., Tse, S., Leblanc, C., Wong, J., Stephens, S. and Feldman, B. M. (2007), The effects of vigorous exercise training on physical function in children with arthritis: A randomized, controlled, SINGLE-BLINDED trial. Arthritis & Rheumatism, 57: 1202–1210. doi: 10.1002/art.23008
ClinicalTrials.gov identifier: NCT00213187. ISRCTN 12040055.
- Issue published online: 28 SEP 2007
- Article first published online: 28 SEP 2007
- Manuscript Accepted: 26 FEB 2007
- Manuscript Received: 20 OCT 2006
- Arthritis Society of Canada
- Canadian Institutes of Health Research
- Canada Arthritis Chair in Childhood Arthritis
- Juvenile idiopathic arthritis;
- Exercise training;
- Randomized controlled trial
To examine the effectiveness of high-intensity aerobic training compared with low-intensity training in terms of energy cost of locomotion, peak oxygen uptake, peak power, and self-reported physical function in children with juvenile idiopathic arthritis (JIA).
Eighty children with JIA, ages 8–16 years, were enrolled in a randomized, single-blind controlled trial. Both groups participated in a 12-week, 3-times–weekly training program consisting of high-intensity aerobics in the experimental group and qigong in the control group. Subjects underwent exercise testing measuring submaximal oxygen uptake at 3 km/hour (VO2submax) as the primary outcome, maximal oxygen uptake, and peak power at the beginning and end of the program. Physical function was measured using the Child Health Assessment Questionnaire (C-HAQ).
The exercise program was well tolerated in both groups. There was no difference in VO2submax or any other exercise testing measures between the groups through the study period and no indication of improvement. Both groups showed significant improvements in C-HAQ with no difference between the groups. Adherence was higher in the control group than the experimental group.
Our findings suggest that activity programs with or without an aerobic training component are safe and may result in an important improvement in physical function. The intensity of aerobic training did not seem to provide any additional benefits, but higher adherence in the qigong program may suggest that less intensive regimens are easier for children with JIA to comply with, and provide a degree of benefit equivalent to more intensive programs.