• 1
    Centers for Disease Control and Prevention (CDC). Prevalence of disabilities and associated health conditions among adults—United States, 1999. MMWR Morb Mortal Wkly Rep 2001; 50: 1205.
  • 2
    Stoddard S, Jans L, Ripple J, Kraus L. Chartbook on work and disability in the United States, 1998: an InfoUse report. US National Institute on Disability and Rehabilitation Research. URL:
  • 3
    Hootman JM, Helmick CG. Projections of US prevalence of arthritis and associated activity limitations. Arthritis Rheum 2006; 54: 2269.
  • 4
    Lawrence RC, Felson DT, Helmick CG, Arnold LM, Choi H, Deyo RA, et al. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: part II. Arthritis Rheum 2008; 58: 2635.
  • 5
    Lawrence RC, Hochberg MC, Kelsey JL, McDuffie FC, Medsger TA Jr, Felts WR, et al. Estimates of the prevalence of selected arthritis and musculoskeletal diseases in the United States. J Rheumatol 1989; 16: 42741.
  • 6
    Lawrence RC, Helmick CG, Arnett FC, Deyo RA, Felson DT, Giannini EH, et al. Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States. Arthritis Rheum 1998; 41: 77899.
  • 7
    Sacks JJ, Harrold LR, Helmick CG, Gurwitz JH, Emani S, Yood RA. Validation of a surveillance case definition for arthritis. J Rheumatol 2005: 32: 3407.
  • 8
    Bombard JM, Powell KE, Martin LM, Helmick CG, Wilson WH. Validity and reliability of self-reported arthritis: Georgia senior centers, 2000–2001. Am J Prev Med 2005; 28: 2518.
  • 9
    Hootman J, Bolen J, Helmick C, Langmaid G. Prevalence of doctor-diagnosed arthritis and arthritis-attributable activity limitation—United States, 2003-2005 [published errata appear in MMWR Morb Mortal Wkly Rep 2006;55:1129 and 2007;56:55]. MMWR Morb Mortal Wkly Rep 2006; 55: 108992.
  • 10
    Bolen J, Sniezek J, Theis K, Helmick C, Hootman J, Brady T, et al. Racial/ethnic differences in the prevalence and impact of doctor-diagnosed arthritis—United States, 2002. MMWR Morb Mortal Wkly Rep 2005; 54: 119123.
  • 11
    Mili F, Helmick CG, Moriarty DG. Health related quality of life among adults reporting arthritis: analysis of data from the Behavioral Risk Factor Surveillance System, US, 1996–1999. J Rheumatol 2003; 30: 1606.
  • 12
    Sacks JJ, Helmick CG, Langmaid G. Deaths from arthritis and other rheumatic conditions, United States, 1979–1998. J Rheumatol 2004; 31: 18238.
  • 13
    Abell JE, Hootman JM, Helmick CG. Prevalence and impact of arthritis among nursing home residents. Ann Rheum Dis 2004; 63: 5914.
  • 14
    Lethbridge-Cejku M, Helmick CG, Popovic JR. Hospitalizations for arthritis and other rheumatic conditions: data from the 1997 National Hospital Discharge Survey. Med Care 2003; 41: 136773.
  • 15
    Hootman JM, Helmick CG, Schappert SM. Magnitude and characteristics of arthritis and other rheumatic conditions on ambulatory medical care visits, United States, 1997. Arthritis Rheum 2002; 47: 57181.
  • 16
    Yelin E, Murphy L, Cisternas MG, Foreman AJ, Pasta DJ, Helmick CG. Medical care expenditures and earnings losses among persons with arthritis and other rheumatic conditions in 2003, and comparisons with 1997. Arthritis Rheum 2007; 56: 1397407.
  • 17
    Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 31524.
  • 18
    Gabriel SE. Classification of rheumatic diseases. In: KlippelJH, DieppePA, editors. Rheumatology. Vol. 2. 2nd ed. London: Mosby; 1998. p. 3.13.4.
  • 19
    Sangha O. Epidemiology of rheumatic diseases. Rheumatology (Oxford) 2000; 39 (Suppl 2): 312.
  • 20
    MacGregor AJ, Silman AJ. A reappraisal of the measurement of disease occurrence in rheumatoid arthritis. J Rheumatol 1992; 19: 11635.
  • 21
    Jacobsson LT, Hanson RL, Knowler WC, Pillemer S, Pettitt DJ, McCance DR, et al. Decreasing incidence and prevalence of rheumatoid arthritis in Pima Indians over a twenty-five–year period. Arthritis Rheum 1994; 37: 115865.
  • 22
    Gabriel SE, Crowson CS, O'Fallon WM. The epidemiology of rheumatoid arthritis in Rochester, Minnesota, 1955–1985. Arthritis Rheum 1999; 42: 41520.
  • 23
    Aho K, Kaipiainen-Seppanen O, Heliovaara M, Klaukka T. Epidemiology of rheumatoid arthritis in Finland. Semin Arthritis Rheum 1998; 27: 32534.
  • 24
    Symmons D, Turner G, Webb R, Asten P, Barrett E, Lunt M, et al. The prevalence of rheumatoid arthritis in the United Kingdom: new estimates for a new century. Rheumatology (Oxford) 2002; 41: 793800.
  • 25
    Rasch EK, Hirsch R, Paulose-Ram R, Hochberg MC. Prevalence of rheumatoid arthritis in persons 60 years of age and older in the United States: effect of different methods of case classification. Arthritis Rheum 2003; 48: 91726.
  • 26
    Del Puente A, Knowler WC, Pettitt DJ, Bennett PH. High incidence and prevalence of rheumatoid arthritis in Pima Indians. Am J Epidemiol 1989; 129: 11708.
  • 27
    Dugowson CE, Koepsell TD, Voigt LF, Bley L, Nelson JL, Daling JR. Rheumatoid arthritis in women: incidence rates in Group Health Cooperative, Seattle, Washington, 1987–1989. Arthritis Rheum 1991; 34: 15027.
  • 28
    Doran MF, Pond GR, Crowson CS, O'Fallon WM, Gabriel SE. Trends in incidence and mortality in rheumatoid arthritis in Rochester, Minnesota, over a forty-year period. Arthritis Rheum 2002; 46: 62531.
  • 29
    Hochberg MC. Changes in the incidence and prevalence of rheumatoid arthritis in England and Wales, 1970–1982. Semin Arthritis Rheum 1990; 19: 294302.
  • 30
    Silman AJ. Has the incidence of rheumatoid arthritis declined in the United Kingdom? Br J Rheumatol 1988; 27: 779.
  • 31
    JRA Criteria Subcommittee of the Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Current proposed revision of the JRA criteria. Arthritis Rheum 1977; 20 Suppl 2: 1959.
  • 32
    EULAR. Nomenclature and classification of arthritis in children. Basel: National Zetung AG 1977; bulletin no. 4.
  • 33
    Petty RE, Southwood TR, Baum J, Bhettay E, Glass DN, Manners P, et al. Revision of the proposed classification criteria for juvenile idiopathic arthritis: Durban, 1997. J Rheumatol 1998; 25: 19914.
  • 34
    Petty RE, Southwood TR, Manners P, Baum J, Glass DN, Goldenberg J, et al. International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001. J Rheumatol 2004; 31: 3902.
  • 35
    Manners PJ, Bower C. Worldwide prevalence of juvenile arthritis: why does it vary so much? J Rheumatol 2002; 29: 152030.
  • 36
    Peterson LS, Mason T, Nelson AM, O'Fallon WM, Gabriel SE. Juvenile rheumatoid arthritis in Rochester, Minnesota 1960–1993: is the epidemiology changing? Arthritis Rheum 1996; 39: 138590.
  • 37
    Malleson PN, Fung MY, Rosenberg AM. The incidence of pediatric rheumatic diseases: results from the Canadian Pediatric Rheumatology Association Disease Registry. J Rheumatol 1996; 23: 19817.
  • 38
    Denardo BA, Tucker LB, Miller LC, Szer IS, Schaller JG, Affiliated Children's Arthritis Centers of New England. Demography of a regional pediatric rheumatology patient population. J Rheumatol 1994; 21: 155361.
  • 39
    Oen K, Fast M, Postl B. Epidemiology of juvenile rheumatoid arthritis in Manitoba, Canada, 1975–92: cycles in incidence. J Rheumatol 1995; 22: 74550.
  • 40
    Oen KG, Cheang M. Epidemiology of chronic arthritis in childhood. Semin Arthritis Rheum 1996; 26: 57591.
  • 41
    Manners PJ, Diepeveen DA. Prevalence of juvenile chronic arthritis in a population of 12-year-old children in urban Australia. Pediatrics 1996; 98: 8490.
  • 42
    Sacks JJ, Helmick CG, Luo YH, Ilowite NT, Bowyer S. Prevalence of and annual ambulatory health care visits for pediatric arthritis and other rheumatologic conditions in the United States in 2001–2004. Arthritis Rheum 2007; 57: 143945.
  • 43
    Alamanos Y, Papadopoulos NG, Voulgari PV, Karakatsanis A, Siozos C, Drosos AA. Epidemiology of ankylosing spondylitis in Northwest Greece, 1983–2002. Rheumatology (Oxford) 2004; 43: 6158.
  • 44
    Braun J, Bollow M, Remlinger G, Eggens U, Rudwaleit M, Distler A, et al. Prevalence of spondylarthropathies in HLA–B27 positive and negative blood donors. Arthritis Rheum 1998; 41: 5867.
  • 45
    Dai SM, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM. Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study. J Rheumatol 2003; 30: 224551.
  • 46
    Carter ET, McKenna CH, Brian DD, Kurland LT. Epidemiology of ankylosing spondylitis in Rochester, Minnesota, 1935–1973. Arthritis Rheum 1979; 22: 36570.
  • 47
    Baum J, Ziff M. The rarity of ankylosing spondylitis in the black race. Arthritis Rheum 1971; 14: 128.
  • 48
    Maurer K. Basic data on arthritis knee, hip, and sacroiliac joints in adults ages 25–74 years. Vital Health Stat 11 1979; 11: 131.
  • 49
    Calin A, Porta J, Fries JF, Schurman DJ. Clinical history as a screening test for ankylosing spondylitis. JAMA 1977; 237: 26134.
  • 50
    Iliopoulos A, Karras D, Ioakimidis D, Arvanitis A, Tsamis N, Iakovou I, et al. Change in the epidemiology of Reiter's syndrome (reactive arthritis) in the post-AIDS era? An analysis of cases appearing in the Greek Army. J Rheumatol 1995; 22: 2524.
  • 51
    Michet CJ, Machado EB, Ballard DJ, McKenna CH. Epidemiology of Reiter's syndrome in Rochester, Minnesota: 1950–1980. Arthritis Rheum 1988; 31: 42831.
  • 52
    Morse HG, Rate RG, Bonnell MD, Kuberski T. High frequency of HLA-B27 and Reiter's syndrome in Navajo Indians. J Rheumatol 1980; 7: 9002.
  • 53
    Boyer GS, Templin DW, Cornoni-Huntley JC, Everett DF, Lawrence RC, Heyse SF, et al. Prevalence of spondyloarthropathies in Alaskan Eskimos. J Rheumatol 1994; 21: 22927.
  • 54
    Shbeeb M, Uramoto KM, Gibson LE, O'Fallon WM, Gabriel SE. The epidemiology of psoriatic arthritis in Olmsted County, Minnesota, USA, 1982–1991. J Rheumatol 2000; 27: 124750.
  • 55
    Loftus EV Jr. Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences. Gastroenterology 2004; 126: 150417.
  • 56
    Palm O, Moum B, Jahnsen J, Gran JT. The prevalence and incidence of peripheral arthritis in patients with inflammatory bowel disease, a prospective population-based study (the IBSEN study). Rheumatology (Oxford) 2001; 40: 125661.
  • 57
    Dekker-Saeys BJ, Meuwissen SG, van den Berg-Loonen EM, de Haas WH, Agenant D, Tytgat GN. Ankylosing spondylitis and inflammatory bowel disease. II. Prevalence of peripheral arthritis, sacroiliitis, and ankylosing spondylitis in patients suffering from inflammatory bowel disease. Ann Rheum Dis 1978; 37: 335.
  • 58
    De Vlam K, Mielants H, Cuvelier C, de Keyser F, Veys EM, de Vos M. Spondyloarthropathy is underestimated in inflammatory bowel disease: prevalence and HLA association. J Rheumatol 2000; 27: 28605.
  • 59
    Steer S, Jones H, Hibbert J, Kondeatis E, Vaughan R, Sanderson J, et al. Low back pain, sacroiliitis, and the relationship with HLA-B27 in Crohn's disease. J Rheumatol 2003; 30: 51822.
  • 60
    Saraux A, Guedes C, Allain J, Devauchelle V, Valls I, Lamour A, et al, Societe de Rhumatologie de l'Ouest.. Prevalence of rheumatoid arthritis and spondyloarthropathy in Brittany, France. J Rheumatol 1999; 26: 26227.
  • 61
    Boyer GS, Templin DW, Bowler A, Lawrence RC, Heyse SP, Everett DF, et al. Spondyloarthropathy in the community: clinical syndromes and disease manifestations in Alaskan Eskimo populations. J Rheumatol 1999; 26: 153744.
  • 62
    Tan EM, Cohen AS, Fries JF, Masi AJ, McShane DJ, Rothfield NF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25: 12717.
  • 63
    Fessel WJ. Systemic lupus erythematosus in the community: incidence, prevalence, outcome, and first symptoms; the high prevalence in black women. Arch Intern Med 1974; 134: 102735.
  • 64
    Uramato KM, Michet CJ Jr, Thumboo J, Sunku J, O'Fallon WM, Gabriel SE. Trends in the incidence and mortality of systemic lupus erythematosus, 1950–1992. Arthritis Rheum 1999; 42: 4650.
  • 65
    McCarty DJ, Manzi S, Medsger TA Jr, Ramsey-Goldman R, LaPorte RE, Kwoh CK. Incidence of systemic lupus erythematosus: race and gender differences. Arthritis Rheum 1995: 38: 126070.
  • 66
    Michet CJ Jr, McKenna CH, Elveback LR, Kaslow RA, Kurland LT. Epidemiology of systemic lupus erythematosus and other connective tissue disease in Rochester, Minnesota, 1950 through 1979. Mayo Clin Proc 1985; 60: 10513.
  • 67
    Balluz L, Philen R, Ortega L, Rosales C, Brock J, Barr D, et al. Investigation of systemic lupus erythematosus in Nogales, Arizona. Am J Epidemiol 2001; 154: 102936.
  • 68
    Maskarinec G, Katz AR. Prevalence of systemic lupus erythematosus in Hawaii: is there a difference between ethnic groups? Hawaii Med J 1995; 54: 4069.
  • 69
    Ward MM. Prevalence of physician-diagnosed systemic lupus erythematosus in the United States: results from the Third National Health and Nutrition Examination Survey. J Womens Health (Larchmt) 2004; 13: 7138.
  • 70
    Subcommittee for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Preliminary criteria for the classification of systemic sclerosis (scleroderma): Arthritis Rheum 1980; 23: 58190.
  • 71
    Winterbauer RH. Multiple telangiectasias, Raynaud's phenomenon, sclerodactyly and subcutaneous calcinosis: a syndrome mimicking hereditary hemorrhagic telangiectasia. Johns Hopkins Hosp Bull 1964; 114: 3619.
  • 72
    Mayes MD, Lacey JV Jr, Beebe-Dimmer J, Gillespie BW, Cooper B, Laing TJ, et al. Prevalence, incidence, survival, and disease characteristics of systemic sclerosis in a large US population. Arthritis Rheum 2003; 48: 224655.
  • 73
    Arnett FC, Howard RF, Tan F, Moulds JM, Bias WB, Durban E, et al. Increased prevalence of systemic sclerosis in a Native American tribe in Oklahoma: association with an Amerindian HLA haplotype. Arthritis Rheum 1996; 39: 136270.
  • 74
    Tan FK, Tercero GM, Arnett FC, Wang N, Chakraborty R. Examination of the possible role of biologically relevant genes around FBN1 in systemic sclerosis in the Choctaw population [letter]. Arthritis Rheum 2003; 48: 32956.
  • 75
    Zhou X, Tan FK, Wang N, Xiong M, Maghidman S, Reveille JD, et al. Genome-wide association study for regions of systemic sclerosis susceptibility in a Choctaw Indian population with high disease prevalence. Arthritis Rheum 2003; 48: 258592.
  • 76
    Tan FK, Wang N, Kuwana M, Chakraborty R, Bona CA, Milewicz DM, et al. Association of fibrillin 1 single-nucleotide polymorphism haplotypes with systemic sclerosis in Choctaw and Japanese populations. Arthritis Rheum 2001; 44: 893901.
  • 77
    Steen VD, Oddis CV, Conte CG, Janoski J, Casterline GZ, Medsger TA Jr. Incidence of systemic sclerosis in Allegheny County, Pennsylvania: a twenty-year study of hospital-diagnosed cases, 1963–1982. Arthritis Rheum 1997; 40: 4415.
  • 78
    Ionnadis JP, Vlachoyiannopoulos PG, Haidich AB, Medsger TA Jr, Lucas M, Michet CJ, et al. Mortality in systemic sclerosis: an international meta-analysis of individual patient data. Am J Med 2005; 118: 210.
  • 79
    Zhang NZ, Shi CS, Yao QP, Pan GX, Wang LL, Wen ZX, et al. Prevalence of primary Sjogren's syndrome in China. J Rheumatol 1995; 22: 65961.
  • 80
    Pillemer SR, Matteson EL, Jacobsson LT, Martens PB, Melton LJ III, O'Fallon WM, et al. Incidence of physician-diagnosed primary Sjogren syndrome in residents of Olmsted County, Minnesota. Mayo Clin Proc 2001; 76: 5939.
  • 81
    Dafni UG, Tzioufas AG, Staikos P, Skopouli FN, Moutsopoulos HM. Prevalence of Sjogren's syndrome in a closed rural community. Ann Rheum Dis 1997; 56: 5215.
  • 82
    Whaley K, Williamson J, Wilson T, McGavin DD, Hughes GR, Hughes H, et al. Sjogren's syndrome and autoimmunity in a geriatric population. Age Ageing 1972; 1: 197206.
  • 83
    Strickland RW, Tesar JT, Berne BH, Hobbs BR, Lewis DM, Welton RC. The frequency of sicca syndrome in an elderly female population. J Rheumatol 1987; 14: 76671.
  • 84
    Drosos AA, Andonopoulos AP, Costopoulos JS, Papadimitriou CS, Moutsopoulos HM. Prevalence of primary Sjogren's syndrome in an elderly population. Br J Rheumatol 1988; 27: 1237.
  • 85
    Jacobsson LT, Axell TE, Hansen BU, Henricsson VJ, Larsson A, Lieberkind K, et al. Dry eyes or mouth—an epidemiological study in Swedish adults, with special reference to primary Sjogren's syndrome. J Autoimmun 1989; 2: 5217.
  • 86
    Bowman SJ, Ibrahim GH, Holmes G, Hamburger J, Ainsworth JR. Estimating the prevalence among Caucasian women of primary Sjogren's syndrome in two general practices in Birmingham, UK. Scand J Rheumatol 2004; 33: 3943.
  • 87
    Melton LD. History of the Rochester Epidemiology Project. Mayo Clin Proc 1996; 71: 26674.
  • 88
    Klein RJ, Schoenborn CA. Age adjustment using the 2000 projected US population. National Center for Health Statistics; January 2001. Healthy people statistical notes, no. 20. URL: