SEARCH

SEARCH BY CITATION

REFERENCES

  • 1
    Harley JB, Kelly JA, Kaufman KM. Unraveling the genetics of systemic lupus erythematosus. Springer Semin Immunopathol 2006; 28: 11930.
  • 2
    Zandman-Goddard G, Shoenfeld Y, Molokhia M, McKeigue P. Infections and SLE. Systemic lupus erythematosus: genes versus environment in high risk populations. Autoimmunity 2005; 38: 47385.
  • 3
    Faria AC, Barcellos KS, Andrade LE. Longitudinal fluctuation of antibodies to extractable nuclear antigens in systemic lupus erythematosus. J Rheumatol 2005; 32: 126772.
  • 4
    Wang CL, Ooi L, Wang F. Prevalence and clinical significance of antibodies to ribonucleoproteins in systemic lupus erythematosus in Malaysia. Br J Rheumatol 1996; 35: 12932.
  • 5
    Migliorini P, Baldini C, Rocchi V, Bombardieri S. Anti-Sm and anti-RNP antibodies. Autoimmunity 2005; 38: 4754.
  • 6
    Hahn BH. An overview of the pathogenesis of systemic lupus erythematosus. In: WallaceDJ, HahnBH, editors. Dubois' lupus erythematosus. 6th ed. Philadelphia: Lippincott Williams & Wilkins; 2002. p. 87.
  • 7
    Ter Borg EJ, Groen H, Horst G, Limburg PC, Wouda AA, Kallenberg CG. Clinical associations of antiribonucleoprotein antibodies in patients with systemic lupus erythematosus. Semin Arthritis Rheum 1990; 20: 16473.
  • 8
    Fatenejad S, Brooks W, Schwartz A, Craft J. Pattern of anti-small nuclear ribonucleoprotein antibodies in MRL/Mp-lpr/lpr mice suggests that the intact U1 snRNP particle is their autoimmunogenic target. J Immunol 1994; 152: 552331.
  • 9
    Greidinger EL, Zang Y, Jaimes K, Hogenmiller S, Nassiri M, Bejarano P, et al. A murine model of mixed connective tissue disease induced with U1 small nuclear RNP autoantigen. Arthritis Rheum 2006; 54: 6619.
  • 10
    Greidinger EL, Hoffman RW. The appearance of U1 RNP antibody specificities in sequential autoimmune human antisera follows a characteristic order that implicates the U1–70 kd and B′/B proteins as predominant U1 RNP immunogens. Arthritis Rheum 2001; 44: 36875.
  • 11
    James JA, Harley JB. Human lupus anti-spliceosome A protein autoantibodies bind contiguous surface structures and segregate into two sequential epitope binding patterns. J Immunol 1996; 156: 401826.
  • 12
    Monneaux F, Muller S. Key sequences involved in the spreading of the systemic autoimmune response to spliceosomal proteins. Scand J Immunol 2001; 54: 4554.
  • 13
    Habets WJ, Sillekens PT, Hoet MH, McAllister G, Lerner MR, van Venrooij WJ. Small nuclear RNA-associated proteins are immunologically related as revealed by mapping of autoimmune reactive B-cell epitopes. Proc Natl Acad Sci U S A 1989; 86: 46748.
  • 14
    James JA, Harley JB. Peptide autoantigenicity of the small nuclear ribonucleoprotein C. Clin Exp Rheumatol 1995; 13: 299305.
  • 15
    Halimi H, Dumortier H, Briand JP, Muller S. Comparison of two different methods using overlapping synthetic peptides for localizing linear B cell epitopes in the U1 snRNP-C autoantigen. J Immunol Methods 1996; 199: 7785.
  • 16
    Misaki Y, Yamamoto K, Yanagi K, Miura H, Ichijo H, Kato T, et al. B cell epitope on the U1 snRNP-C autoantigen contains a sequence similar to that of the herpes simplex virus protein. Eur J Immunol 1993; 23: 106471.
  • 17
    Hoet RM, Raats JM, de Wildt R, Dumortier H, Muller S, van den Hoogen F, et al. Human monoclonal autoantibody fragments from combinatorial antibody libraries directed to the U1snRNP associated U1C protein; epitope mapping, immunolocalization and V-gene usage. Mol Immunol 1998; 35: 104555.
  • 18
    James JA, Scofield RH, Harley JB. Basic amino acids predominate in the sequential autoantigenic determinants of the small nuclear 70K ribonucleoprotein. Scand J Immunol 1994; 39: 55766.
  • 19
    Guldner HH, Netter HJ, Szostecki C, Lakomek HJ, Will H. Epitope mapping with a recombinant human 68-kDa (U1) ribonucleoprotein antigen reveals heterogeneous autoantibody profiles in human autoimmune sera. J Immunol 1988; 141: 46975.
  • 20
    Cram DS, Fisicaro N, Coppel RL, Whittingham S, Harrison LC. Mapping of multiple B cell epitopes on the 70-kilodalton autoantigen of the U1 ribonucleoprotein complex. J Immunol 1990; 145: 6305.
  • 21
    Nyman U, Lundberg I, Hedfors E, Pettersson I. Recombinant 70-kD protein used for determination of autoantigenic epitopes recognized by anti-RNP sera. Clin Exp Immunol 1990; 81: 528.
  • 22
    Takeda Y, Nyman U, Winkler A, Wise KS, Hoch SO, Pettersson I, et al. Antigenic domains on the U1 small nuclear ribonucleoprotein-associated 70K polypeptide: a comparison of regions selectively recognized by human and mouse autoantibodies and by monoclonal antibodies. Clin Immunol Immunopathol 1991; 61: 5568.
  • 23
    James JA, Harley JB. Linear epitope mapping of an Sm B/B′ polypeptide. J Immunol 1992; 148: 20749.
  • 24
    Arbuckle MR, Schilling AR, Harley JB, James JA. A limited lupus anti-spliceosomal response targets a cross-reactive, proline-rich motif. J Autoimmun 1998; 11: 4318.
  • 25
    Arbuckle MR, Reichlin M, Harley JB, James JA. Shared early autoantibody recognition events in the development of anti-Sm B/B′ in human lupus. Scand J Immunol 1999; 50: 44755.
  • 26
    James JA, Gross T, Scofield RH, Harley JB. Immunoglobulin epitope spreading and autoimmune disease after peptide immunization: Sm B/B′-derived PPPGMRPP and PPPGIRGP induce spliceosome autoimmunity. J Exp Med 1995; 181: 45361.
  • 27
    McClain MT, Heinlen LD, Dennis GJ, Roebuck J, Harley JB, James JA. Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry. Nat Med 2005; 11: 859.
  • 28
    McCluskey J, Farris AD, Keech CL, Purcell AW, Rischmueller M, Kinoshita G, et al. Determinant spreading: lessons from animal models and human disease. Immunol Rev 1998; 164: 20929.
  • 29
    Hochberg MC, for the Diagnostic and Therapeutic Criteria Committee of the American College of Rheumatology. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [letter]. Arthritis Rheum 1997; 40: 1725.
  • 30
    Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ, Rothfield NF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25: 12717.
  • 31
    Maddison PJ, Mogavero H, Reichlin M. Patterns of clinical disease associated with antibodies to nuclear ribonucleoprotein. J Rheumatol 1978; 5: 40711.
  • 32
    McClain MT, Ramsland PA, Kaufman KM, James JA. Anti-Sm autoantibodies in systemic lupus target highly basic surface structures of complexed spliceosomal autoantigens. J Immunol 2002; 168: 205462.
  • 33
    Lutz CS, Murthy KG, Schek N, O'Connor JP, Manley JL, Alwine JC. Interaction between the U1 snRNP-A protein and the 160-kD subunit of cleavage-polyadenylation specificity factor increases polyadenylation efficiency in vitro. Genes Dev 1996; 10: 32537.
  • 34
    Theissen H, Etzerodt M, Reuter R, Schneider C, Lottspeich F, Argos P, et al. Cloning of the human cDNA for the U1 RNA-associated 70K protein. EMBO Journal 1986; 5: 320917.
  • 35
    Sillekens PT, Beijer RP, Habets WJ, van Venrooij WJ, Nelissen RL, Geurts van Kessel AH. Human U1 snRNP-specific C protein: complete cDNA and protein sequence and identification of a multigene family in mammals. Nucleic Acids Res 1988; 16: 830721.
  • 36
    Nelissen RL, Sillekens PT, Beijer RP, Geurts van Kessel AH, van Venrooij WJ. Structure, chromosomal localization and evolutionary conservation of the gene encoding human U1 snRNP-specific A protein. Gene 1991; 102: 18996.
  • 37
    Arbuckle MR, Reichlin M, Harley JB, James JA. The development of lupus humoral autoimmunity for anti-Sm autoantibodies is consistent with predictable sequential B cell epitope spreading. Scand J Immunol 1999; 50: 44755.
  • 38
    Deshmukh US, Bagavant H, Sim D, Pidiyar V, Fu SM. A SmD peptide induces better antibody responses to other proteins within the small nuclear ribonucleoprotein complex than to SmD protein via intermolecular epitope spreading. J Immunol 2007; 178: 256571.
  • 39
    Deshmukh US, Kannapell CC, Fu SM. Immune responses to small nuclear ribonucleoproteins: antigen-dependent distinct B cell epitope spreading patterns in mice immunized with recombinant polypeptides of small nuclear ribonucleoproteins. J Immunol 2002; 168: 532632.
  • 40
    Poole BD, Scofield RH, Harley JB, James JA. Epstein-Barr virus and molecular mimicry in systemic lupus erythematosus. Autoimmunity 2006; 39: 6370.
  • 41
    Williams DG, Sharpe NG, Wallace G, Latchman DS. A repeated proline-rich sequence in Sm B/B′ and N is a dominant epitope recognized by human and murine autoantibodies. J Autoimmun 1990; 3: 71525.
  • 42
    James JA, Harley JB. A model of peptide-induced lupus autoimmune B cell epitope spreading is strain specific and is not H-2 restricted in mice. J Immunol 1998; 160: 5028.
  • 43
    Burdt MA, Hoffman RW, Deutscher SL, Wang GS, Johnson JC, Sharp GC. Long-term outcome in mixed connective tissue disease: longitudinal clinical and serologic findings. Arthritis Rheum 1999; 42: 899909.
  • 44
    Luyckx A, Westhovens R, Oris E, Papisch W, Bossuyt X. Clinical relevance of measurement of antibodies to individual snU1-RNP proteins. Clin Chem 2005; 51: 188890.
  • 45
    Query CC, Keene JD. A human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen. Cell 1987; 51: 21120.
  • 46
    Harley JB, James JA. Epstein-Barr virus infection may be an environmental risk factor for systemic lupus erythematosus in children and teenagers [letter]. Arthritis Rheum 1999; 42: 17823.
  • 47
    James JA, Neas BR, Moser KL, Hall T, Bruner GR, Sestak AL, et al. Systemic lupus erythematosus in adults is associated with previous Epstein-Barr virus exposure. Arthritis Rheum 2001; 44: 11226.
  • 48
    James JA, Scofield RH, Harley JB. Lupus humoral autoimmunity after short peptide immunization. Ann N Y Acad Sci 1997; 815: 1247.
  • 49
    Arbuckle MR, Gross T, Scofield RH, Hinshaw LB, Chang AC, Taylor FB Jr, et al. Lupus humoral autoimmunity induced in a primate model by short peptide immunization. J Investig Med 1998; 46: 5865.
  • 50
    Sundar K, Jacques S, Gottlieb P, Villars R, Benito ME, Taylor DK, et al. Expression of the Epstein-Barr virus nuclear antigen-1 (EBNA-1) in the mouse can elicit the production of anti-dsDNA and anti-Sm antibodies. J Autoimmun 2004; 23: 12740.
  • 51
    Arbuckle MR, McClain MT, Rubertone MV, Scofield RH, Dennis GJ, James JA, et al. Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med 2003; 349: 152633.