Rheumatoid Arthritis Basic Science Studies

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The α7 nicotinic acetylcholine receptor on fibroblast-like synoviocytes and in synovial tissue from rheumatoid arthritis patients: A possible role for a key neurotransmitter in synovial inflammation

  1. Marjolein A. Van Maanen1,
  2. Susanne P. Stoof2,
  3. Esmerij P. Van Der Zanden1,
  4. Wouter J. De Jonge1,
  5. Richard A. Janssen3,†,
  6. David F. Fischer3,‡,
  7. Nick Vandeghinste4,
  8. Reginald Brys4,
  9. Margriet J. Vervoordeldonk2,§,
  10. Paul P. Tak1,§,*

Article first published online: 29 APR 2009

DOI: 10.1002/art.24470

Issue

Arthritis & Rheumatism

Arthritis & Rheumatism

Volume 60, Issue 5, pages 1272–1281, May 2009

Additional Information

How to Cite

Maanen, M. A. V., Stoof, S. P., Zanden, E. P. V. D., Jonge, W. J. D., Janssen, R. A., Fischer, D. F., Vandeghinste, N., Brys, R., Vervoordeldonk, M. J. and Tak, P. P. (2009), The α7 nicotinic acetylcholine receptor on fibroblast-like synoviocytes and in synovial tissue from rheumatoid arthritis patients: A possible role for a key neurotransmitter in synovial inflammation. Arthritis & Rheumatism, 60: 1272–1281. doi: 10.1002/art.24470

Author Information

  1. 1

    Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

  2. 2

    Academic Medical Center, University of Amsterdam, and Arthrogen BV, Amsterdam, The Netherlands

  3. 3

    BioFocus DPI, a Galapagos company, Leiden, The Netherlands

  4. 4

    Galapagos, Mechelen, Belgium

  1. †

    Dr. Janssen owns stock options in Galapagos.

  2. ‡

    Dr. Fischer owns stock and stock options in Galapagos.

  3. §

    Drs. Vervoordeldonk and Tak contributed equally to this work.

*Division of Clinical Immunology and Rheumatology, F4-218, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands

Publication History

  1. Issue published online: 29 APR 2009
  2. Article first published online: 29 APR 2009
  3. Manuscript Accepted: 31 JAN 2009
  4. Manuscript Received: 10 JUL 2008

Funded by

  • Top Institute Pharma. Grant Number: T1-215
  • Netherlands Organization for Scientific Research (grants NWO and VIDI)

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