Fibrosis

You have full text access to this OnlineOpen article

Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation

  1. David Lagares1,
  2. Oscar Busnadiego2,
  3. Rosa Ana García-Fernández3,
  4. Mohit Kapoor4,
  5. Shangxi Liu5,
  6. David E. Carter6,
  7. David Abraham7,
  8. Xu Shi-Wen7,
  9. Patricia Carreira8,
  10. Benjamin A. Fontaine9,
  11. Barry S. Shea9,
  12. Andrew M. Tager9,†,
  13. Andrew Leask5,‡,
  14. Santiago Lamas1,‡,
  15. Fernando Rodríguez-Pascual2,‡,*

Article first published online: 26 APR 2012

DOI: 10.1002/art.33482

Issue

Arthritis & Rheumatism

Arthritis & Rheumatism

Volume 64, Issue 5, pages 1653–1664, May 2012

Additional Information

How to Cite

Lagares, D., Busnadiego, O., García-Fernández, R. A., Kapoor, M., Liu, S., Carter, D. E., Abraham, D., Shi-Wen, X., Carreira, P., Fontaine, B. A., Shea, B. S., Tager, A. M., Leask, A., Lamas, S. and Rodríguez-Pascual, F. (2012), Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation. Arthritis & Rheumatism, 64: 1653–1664. doi: 10.1002/art.33482

Author Information

  1. 1

    Centro de Biología Molecular Severo Ochoa, CSIC and Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain

  2. 2

    Centro de Biología Molecular Severo Ochoa, CSIC and Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain, and Centro de Investigación Cardiovascular, CSIC and Institut Català de Ciències Cardiovasculars, Barcelona, Spain

  3. 3

    Universidad Complutense de Madrid, Madrid, Spain

  4. 4

    University of Montreal Hospital Research Center, Montreal, Quebec, Canada

  5. 5

    University of Western Ontario, London, Ontario, Canada

  6. 6

    London Regional Genomics Centre, London, Ontario, Canada

  7. 7

    University College London, Royal Free Campus, London, UK

  8. 8

    Hospital Universitario 12 de Octubre, Madrid, Spain

  9. 9

    Massachusetts General Hospital, Charlestown

  1. †

    Dr. Tager has received an honorarium from Pfizer (less than $10,000).

  2. ‡

    Drs. Leask, Lamas, and Rodríguez-Pascual contributed equally to this work.

*Centro de Biología Molecular Severo Ochoa, CSIC, Universidad Autónoma de Madrid, Nicolás Cabrera, 1 E-28049, Madrid, Spain

  1. †

    Dr. Tager has received an honorarium from Pfizer (less than $10,000).

  2. ‡

    Drs. Leask, Lamas, and Rodríguez-Pascual contributed equally to this work.

Publication History

  1. Issue published online: 26 APR 2012
  2. Article first published online: 26 APR 2012
  3. Accepted manuscript online: 15 NOV 2011 12:36PM EST
  4. Manuscript Accepted: 9 NOV 2011
  5. Manuscript Received: 6 JUL 2011

Funded by

  • Ministerio de Ciencia e Innovación
  • Plan Nacional de I+D+I. Grant Numbers: SAF2006-02410, SAF2009-09085, SAF2009-07520, Consolider CSD-2007-0020: ROSASNET
  • Comunidad Autónoma de Madrid (CARDIOVREP Consortium)
  • Sociedad Española de Nefrología (Senefro grant)
  • Fundación Médica Mutua Madrileña (Fundación MM grant)
  • Fundación Genoma España (Meica project)
  • Canadian Institutes of Health Research
  • Canadian Foundation for Innovation
  • Ontario Thoracic Society
  • NIH. Grant Numbers: R01-HL-095732, K08-HL-105656

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article with Supporting Information (HTML) Get PDF (1479K)

Additional Supporting Information may be found in the online version of this article.

FilenameFormatSizeDescription
ART_33482_sm_SupplTable1.doc38KSupplementary Table 1
ART_33482_sm_SupplTable2.doc36KSupplementary Table 2

Please note: Wiley-Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

View Full Article with Supporting Information (HTML) Get PDF (1479K)